Fiber-Optic Raman Spectroscopy with Nature-Inspired Genetic Algorithms Enhances Real-Time in Vivo Detection and Diagnosis of Nasopharyngeal Carcinoma

• Published in: Analytical chemistry (Washington) Vol. 91; no. 13; pp. 8101 - 8108
• Main Authors: Žuvela, Petar, Lin, Kan, Shu, Chi, Zheng, Wei, Lim, Chwee Ming, Huang, Zhiwei
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 02.07.2019
• Subjects: Algorithms; Analytical chemistry; Biomedical materials; carcinoma; Chemistry; Conformation; Diagnosis; Diagnostic systems; Discriminant analysis; Endoscopy; Fiber optics; Genetic algorithms; Genetic analysis; Lipids; Nasopharyngeal carcinoma; Nucleic acids; Optical fibers; patients; Phenylalanine; porphyrins; Proteins; Raman spectra; Raman spectroscopy; Real time; Spectroscopy; Spectrum analysis; Statistical analysis; Throat cancer; Tryptophan; Wavelengths

Raman spectroscopy is an optical vibrational spectroscopic technique capable of probing specific biochemical structures and conformation of tissue and cells in biomedical systems. This work aims to assess the clinical utility of a fiber-optic Raman spectroscopy with nature-inspired genetic algorithm...