Production of Site-Specific Antibody–Drug Conjugates Using Optimized Non-Natural Amino Acids in a Cell-Free Expression System - Zimmerman, Erik S; Heibeck, Tyler H; Gill, Avinash; Li, Xiaofan; Murray, Christopher J; Madlansacay, Mary Rose; Tran, Cuong; Uter, Nathan T; Yin, Gang; Rivers, Patrick J; Yam, Alice Y; Wang, Willie D; et al. (Bioconjugate chemistry, 2014)
Keywords: Amino acids; Amino Acids - chemistry; Antigens; Biochemical Research Methods; Biochemistry & Molecular Biology; Cell Line; Cell-Free System; Chemistry; Chemistry, Multidisciplinary; Chemistry, Organic; Chromatography, Liquid; Cytotoxicity; Gene expression; Genetics; High-Throughput Screening Assays; Humans; Immunoconjugates - chemistry; Immunoconjugates - pharmacology; Immunogenicity; Life Sciences & Biomedicine; Molecules; Pharmacokinetics; Physical Sciences; Protein synthesis; Science & Technology; Tandem Mass Spectrometry; Tumors; GENETIC-CODE; EVOLUTION; EFFICACY; TRANSFER-RNA SYNTHETASE; STABILITY; CYTOTOXIC DRUG; COPPER-FREE; PROTEINS; CANCER; PAIR