Investigation of Environmental Pollutant-Induced Lung Inflammation and Injury in a 3D Coculture-Based Microfluidic Pulmonary Alveolus System - Zhang, Fen; Liu, Wenming; Zhou, Sisi; Jiang, Ling; Wang, Kan; Wei, Yuanqing; Liu, Anran; Wei, Wei; Liu, Songqin (Analytical chemistry (Washington), 2020)
Keywords: Alveoli; analytical chemistry; Benzopyrenes - adverse effects; Benzopyrenes - chemistry; Biomimetics; Cells, Cultured; Chemistry; coculture; Coculture Techniques; Computer simulation; Cytokines - analysis; Cytokines - metabolism; drugs; Endothelium; Environmental impact; Environmental monitoring; Environmental Pollutants - adverse effects; Environmental Pollutants - chemistry; Epithelium; Human pathology; Humans; Inflammation; Injuries; Injury analysis; Interfaces; Lungs; Microenvironments; Microfluidic Analytical Techniques; Microfluidics; Microscopy, Confocal; Microvasculature; Molecular Structure; Monoculture; Nicotine - adverse effects; Nicotine - chemistry; pathophysiology; Pneumonia - chemically induced; Pneumonia - metabolism; Pneumonia - pathology; Pollutants; pollution; Pulmonary Alveoli - drug effects; Pulmonary Alveoli - metabolism; Pulmonary Alveoli - pathology; Reactive Oxygen Species - metabolism; Synergistic effect; Tissue engineering; viability