Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses - Rotroff, Daniel M; Martin, Matt T; Dix, David J; Filer, Dayne L; Houck, Keith A; Knudsen, Thomas B; Sipes, Nisha S; Reif, David M; Xia, Menghang; Huang, Ruili; Judson, Richard S (Environmental science & technology, 2014)
Keywords: agonists; Algorithms; Animals; antagonists; Biological Assay; cell growth; Chemicals; drugs; Endocrine Disruptors - analysis; Endocrine system; endocrine-disrupting chemicals; Estrogen Antagonists - analysis; Estrogen Receptor alpha - agonists; Estrogen Receptor alpha - antagonists & inhibitors; Estrogen Receptor beta - agonists; Estrogen Receptor beta - antagonists & inhibitors; estrogen receptors; Estrogens; Estrogens - analysis; Food additives; High-Throughput Screening Assays; Humans; in vitro studies; inert ingredients; MCF-7 Cells; Models, Chemical; Pesticides; prioritization; screening; Sensitivity analysis; Signal Transduction