Enhanced Photon Emission of Chemiluminescent Luminophore for Ultra-Fast and Semi-Automatic Immunoassay toward Single Molecule Detection

• Published in: Analytical chemistry (Washington) Vol. 95; no. 20; pp. 8070 - 8076
• Main Authors: Ren, Xiaoxuan, Gao, Xuwen, Zou, Guizheng
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 23.05.2023
• Subjects: Amplification; analytical chemistry; Antigens; Cadmium Compounds - chemistry; Chemical bonds; Chemiluminescence; Chemistry; Commercialization; detection limit; Emissions; energy; Immunoassay; Immunoassays; Immunodiagnosis; Luminescent Measurements; Nanocrystals; Photon emission; Photons; Potassium permanganate; Quantum Dots; serodiagnosis; stabilizers; Tellurium - chemistry; Thyroid; Thyroid-stimulating hormone; Thyrotropin

Optical single molecule detection is normally achieved via amplifying the total emission of photons of luminophores and is strongly anticipated to extend the commercialized application of chemiluminescence (CL). To overcome the limited CL photons of molecule luminophores, herein, a nanocrystal (NC)...