A β-Amino Acid Containing Tripeptide from a Pseudomonas − Alteromonas Bacterium Associated with a Black Sea Sponge

• Published in: Journal of natural products (Washington, D.C.) Vol. 63; no. 10; pp. 1454 - 1455
• Main Authors: De Rosa, Salvatore, De Giulio, Alfonso, Tommonaro, Giuseppina, Popov, Simeon, Kujumgiev, Athanas
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 01.10.2000; Amer Chemical Soc; American Society of Pharmacognosy
• Subjects: Alteromonas; Alteromonas - chemistry; Amino Acids - chemistry; Animals; Bacteriology; beta -aminopimelic acid; Biological and medical sciences; Chemistry, Medicinal; Dysidea fragilis; Fundamental and applied biological sciences. Psychology; Life Sciences & Biomedicine; Marine; Microbiology; Morphology, structure, chemical composition; Oligopeptides - chemistry; Oligopeptides - isolation & purification; Pharmacology & Pharmacy; Plant Sciences; Porifera - microbiology; Pseudomonas; Pseudomonas - chemistry; Science & Technology; tripeptides; Black Sea; MED, Black Sea; FATTY-ACIDS; MARINE SPONGE; Pseudomonadales; Host; Pseudomonas; Alteromonas; Pseudopeptide; Marine environment; Microbial origin; Porifera; Aminoacid; Bacteria; Pseudomonadaceae; Benzenic compound; Dicarboxylic acid; Isolation; Invertebrata; Structural analysis
• ISSN: 0163-3864; 1520-6025
• DOI: 10.1021/np0002132

A novel tripeptide, 1, was isolated from the extracellular extract of a Pseudomonas − Alteromonas bacterium that was associated with the Black Sea sponge Dysidea fragilis. Compound 1 contains the novel β-aminopimelic acid described for the first time from a natural product. The structure of 1 is suggested on the basis of the analysis of spectroscopic data and chemical degradation.