Mass Spectrometry Uncovers the Role of Surfactin as an Interspecies Recruitment Factor

• Published in: ACS chemical biology Vol. 14; no. 3; pp. 459 - 467
• Main Authors: Luzzatto-Knaan, Tal, Melnik, Alexey V, Dorrestein, Pieter C
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 15.03.2019
• Subjects: Bacillus subtilis; Bacterial Proteins - isolation & purification; Biological Products - isolation & purification; Cells, Cultured; Chromatography, High Pressure Liquid; Coculture Techniques; Lipopeptides - isolation & purification; Paenibacillus; Peptides, Cyclic - isolation & purification; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods; Tandem Mass Spectrometry

Microbes use metabolic exchange to sense and respond to their changing environment. Surfactins, produced by Bacillus subtilis, have been extensively studied for their role in biofilm formation, biosurfactant properties, and antimicrobial activity, affecting the surrounding microbial consortia. Using...