Metabolic Engineering of Yarrowia lipolytica for Conversion of Waste Cooking Oil into Omega‑3 Eicosapentaenoic Acid

• Published in: ACS Engineering Au Vol. 5; no. 2; pp. 128 - 139
• Main Authors: Qin, Jiansong, Liu, Na, Abid, Umer, Coleman, Sarah M., Wang, Yongdan, Fu, Qiang, Yoon, Seongkyu, Alper, Hal S., Xie, Dongming
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 16.04.2025
• Subjects: eicosapentaenoic acid; omega-3 fatty acids; triglycerides; waste cooking oil; Yarrowia lipolytica

Omega-3 polyunsaturated fatty acids (PUFAs), especially eicosapentaenoic acid (EPA, C20:5), are crucial dietary fats known for their numerous health benefits. However, traditional sources of EPA, like fish oil, raise sustainability and environmental concerns, underscoring the need for alternative pr...