Molecularly Engineered “Janus GroEL”: Application to Supramolecular Copolymerization with a Higher Level of Sequence Control

• Published in: Journal of the American Chemical Society Vol. 142; no. 31; pp. 13310 - 13315
• Main Authors: Kashiwagi, Daiki, Shen, Hao K, Sim, Seunghyun, Sano, Koki, Ishida, Yasuhiro, Kimura, Ayumi, Niwa, Tatsuya, Taguchi, Hideki, Aida, Takuzo
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 05.08.2020

Herein we report the synthesis and isolation of a shape-persistent Janus protein nanoparticle derived from the biomolecular machine chaperonin GroEL ( A GroEL B ) and its application to DNA-mediated ternary supramolecular copolymerization. To synthesize A GroEL B with two different DNA strands A and...