Characterization of Glycoproteins in Pancreatic Cyst Fluid Using a High-Performance Multiple Lectin Affinity Chromatography Platform

• Published in: Journal of proteome research Vol. 13; no. 1; pp. 289 - 299
• Main Authors: Gbormittah, Francisca Owusu, Haab, Brian B, Partyka, Katie, Garcia-Ott, Carolina, Hancapie, Marina, Hancock, William S
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 03.01.2014
• Subjects: Chromatography, Affinity - methods; Electrophoresis, Polyacrylamide Gel; Glycoproteins - metabolism; Humans; Lectins - metabolism; Mass Spectrometry - methods; Pancreatic Cyst - metabolism; pancreatic cancer; glycoproteins; biomarker discovery; pancreatic cyst fluid; mucinous cyst; nonmucinous cyst

Currently, pancreatic cancer is the fourth cause of cancer death. In 2013, it is estimated that ∼38 460 people will die of pancreatic cancer. Early detection of malignant cyst (pancreatic cancer precursor) is necessary to help prevent late diagnosis of the tumor. In this study, we characterized glyc...