EzrA promotes Z-ring formation through interaction of its QNR motif with FtsA

• Published in: Journal of bacteriology Vol. 207; no. 7; p. e0012525
• Main Authors: Li, Tingting, Liu, Xiujian, Zhang, Liangsheng, Li, Haotian, Ni, Minghui, Zou, Wenjin, Liang, Menglei, Gong, Ruotong, Hu, Qiao, Zhao, Lelin, Hu, Zhe, Li, Lu, Huang, Qi, Zhou, Rui
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 24.07.2025
• Subjects: Amino Acid Motifs; Bacterial Proteins - chemistry; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Bacteriology; Cell Division; Cytoskeletal Proteins - genetics; Cytoskeletal Proteins - metabolism; Gene Expression Regulation, Bacterial - physiology; Immunoprecipitation; Localization; Molecular modelling; Protein Binding; Proteins; Research Article; Streptococcus suis - genetics; Streptococcus suis - metabolism; cell division; interaction; Streptococcus; FtsZ; EzrA; FtsA

Bacteria replicate through binary fission in which the FtsZ-ring positioning and assembly is a crucial process requiring precise spatial and temporal regulation. However, the mechanism of this process remains largely unknown, especially in ovoid-shaped bacteria, such as Streptococci, in which many m...