Ion−π Interactions in Ligand Design for Anions and Main Group Cations

• Published in: Accounts of chemical research Vol. 46; no. 4; pp. 955 - 966
• Main Authors: Watt, Michelle M, Collins, Mary S, Johnson, Darren W
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 16.04.2013
• Subjects: Anions; Anions - chemistry; Attraction; Binding; Binding Sites; Cations; Cations - chemistry; Centroids; Design engineering; Hydrogen Bonding; Ligands; Models, Molecular; Transport

Interactions between ions and aromatic rings are now a mainstay in the field of supramolecular chemistry. The prototypical cation−π interaction, first characterized in the gas phase, is now well-known as an important contributor to protein structure and enzyme function and as a noncovalent force fou...