Design, Synthesis, and Insecticidal Activity of Novel Pyrazole Derivatives Containing α-Hydroxymethyl-N-benzyl Carboxamide, α-Chloromethyl-N-benzyl Carboxamide, and 4,5-Dihydrooxazole Moieties

• Published in: Journal of agricultural and food chemistry Vol. 60; no. 6; pp. 1470 - 1479
• Main Authors: Song, Hongjian, Liu, Yuxiu, Xiong, Lixia, Li, Yongqiang, Yang, Na, Wang, Qingmin
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 15.02.2012; Amer Chemical Soc
• Subjects: Agriculture; Agriculture, Multidisciplinary; Animals; antifeeding activity; Aphids; Aphis craccivora; Aphis fabae; Biological and medical sciences; chemical synthesis; Chemistry; Chemistry, Applied; Control; Culex; Culex pipiens pallens; Drug Design; Food industries; Food Science & Technology; Fundamental and applied biological sciences. Psychology; Helicoverpa armigera; insecticidal properties; Insecticides; Insecticides - chemical synthesis; Insecticides - chemistry; Integrated pest control; Lepidoptera; Life Sciences & Biomedicine; Molecular Structure; Moths; nuclear magnetic resonance spectroscopy; Physical Sciences; Phytopathology. Animal pests. Plant and forest protection; Plutella xylostella; Protozoa. Invertebrates; Pyrazoles; Pyrazoles - chemical synthesis; Pyrazoles - chemistry; Science & Technology; Tetranychidae; Tetranychus cinnabarinus; pyrazole-5-carboxamide; 4,5-dihydrooxazole; antifeedant activity; insecticidal activity; α-hydroxymethyl-N-benzyl; α-chloromethyl-N-benzyl; alpha-chloromethyl-N-benzyl; alpha-hydroxymethyl-N-benzyl; ACARICIDAL ACTIVITY; RESISTANCE; DISCOVERY; Design; Insecticide; Synthesis; 4,5-dihydrooxazok; Pesticides; Antifeedant; Carboxamide

On the basis of commercial insecticides tebufenpyrad and tolfenpyrad, two series of novel pyrazole-5-carboxamides containing α-hydroxymethyl-N-benzyl or α-chloromethyl-N-benzyl and pyrazoles containing 4,5-dihydrooxazole moieties were designed and synthesized via the key intermediate 2-amino-1-(4-su...