Effect of Citalopram on Agitation in Alzheimer Disease: The CitAD Randomized Clinical Trial - Porsteinsson, Anton P; Drye, Lea T; Pollock, Bruce G; Devanand, D. P; Frangakis, Constantine; Ismail, Zahinoor; Marano, Christopher; Meinert, Curtis L; Mintzer, Jacobo E; Munro, Cynthia A; Pelton, Gregory; Rabins, Peter V; et al. (JAMA : the journal of the American Medical Association, 2014)
Keywords: Activities of Daily Living; Adult and adolescent clinical studies; Aged; Aged, 80 and over; Alzheimer Disease - complications; Alzheimer Disease - nursing; Alzheimer Disease - physiopathology; Alzheimer's disease; Arrhythmias, Cardiac - chemically induced; Biological and medical sciences; Caregivers - psychology; Citalopram - adverse effects; Citalopram - therapeutic use; Clinical trials; Cognition - drug effects; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Double-Blind Method; Drug therapy; Drugs; Female; General aspects; Humans; Male; Medical sciences; Neurology; Organic mental disorders. Neuropsychology; Psychology. Psychoanalysis. Psychiatry; Psychomotor Agitation - drug therapy; Psychomotor Agitation - etiology; Psychopathology. Psychiatry; Serotonin Uptake Inhibitors - adverse effects; Serotonin Uptake Inhibitors - therapeutic use; Severity of Illness Index; Stress, Psychological; Treatment Outcome; Nervous system diseases; Agitation; Serotonin; Alzheimer disease; Psychotropic; Reuptake inhibitor; Selective serotonin reuptake inhibitor; Cerebral disorder; Citalopram; Medicine; Central nervous system disease; Neurotransmitter; Antidepressant agent; Clinical trial; Degenerative disease