Bioavailability of Anthocyanins and Ellagitannins Following Consumption of Raspberries by Healthy Humans and Subjects with an Ileostomy

• Published in: Journal of agricultural and food chemistry Vol. 58; no. 7; pp. 3933 - 3939
• Main Authors: González-Barrio, Rocío, Borges, Gina, Mullen, William, Crozier, Alan
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Washington, DC American Chemical Society 14.04.2010
• Subjects: administration & dosage; Adult; anthocyanins; Anthocyanins - administration & dosage; Anthocyanins - blood; Anthocyanins - pharmacokinetics; Anthocyanins - urine; bioavailability; biodegradation; Biological and medical sciences; Biological Availability; blood; blood plasma; chemical degradation; chemistry; diet; digestion; digestive juices; ellagic acid; ellagic acid-O-glucuronide; excretion; Feeding. Feeding behavior; Female; Food industries; Fruit and vegetable industries; Fundamental and applied biological sciences. Psychology; Health Status; human nutrition; Humans; Hydrolyzable Tannins; Hydrolyzable Tannins - administration & dosage; Hydrolyzable Tannins - blood; Hydrolyzable Tannins - pharmacokinetics; Hydrolyzable Tannins - urine; ileal fluid; Ileostomy; ileum; Intestinal Absorption; Intestine, Small; Intestine, Small - metabolism; Male; metabolism; metabolites; Middle Aged; nutrition physiology; patients; pharmacokinetics; phytochemicals; Plant Extracts; Plant Extracts - administration & dosage; Plant Extracts - blood; Plant Extracts - pharmacokinetics; Plant Extracts - urine; raspberries; Rosaceae; Rosaceae - chemistry; sanguiin H-6; surgery; tannins; urine; urolithin B-O-glucuronide; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Ellagitannins; anthocyanins; bioavailability; urolithins; colonic metabolites; metabolism; ellagic acid; raspberries; Anthocyanin; Consumption; Human; Fruit; Healthy subject; Metabolite; Bioavailability; Metabolism; Flavonoid; Polyphenol; Ellagic acid; Raspberry; Pigments

The fate of anthocyanins, ellagic acid, and ellagitannins was studied following the consumption of 300 g of raspberries by healthy human volunteers and subjects with an ileostomy. Postingestion plasma and urine from the former and ileal fluid and urine from the latter group were collected and analyz...