Orthogonal Discrimination among Functional Groups in Ullmann-Type C–O and C–N Couplings

• Published in: Journal of organic chemistry Vol. 81; no. 17; pp. 7315 - 7325
• Main Authors: Rovira, Mireia, Soler, Marta, Güell, Imma, Wang, Ming-Zheng, Gómez, Laura, Ribas, Xavi
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 02.09.2016; Amer Chemical Soc
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; NITROGEN-CONTAINING HETEROCYCLES; ROOM-TEMPERATURE; MILD CONDITIONS; CATALYZED CROSS-COUPLINGS; ARYL HALIDES; COPPER; AMIDE BOND FORMATION; VINYL HALIDES; HIGHLY EFFICIENT; ALKYL-HALIDES

The copper-catalyzed arylation of nucleophiles has been established as an efficient methodology for the formation of C–C and C–heteroatom bonds. Considering the advances during the last two decades, the ligand choice plays a key role in such transformations and can strongly influence the catalytic e...