TBAI-Catalyzed Reaction between N‑Tosylhydrazones and Sulfur: A Procedure toward 1,2,3-Thiadiazole

• Published in: Journal of organic chemistry Vol. 81; no. 1; pp. 271 - 275
• Main Authors: Chen, Jiangfei, Jiang, Yan, Yu, Jin-Tao, Cheng, Jiang
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 04.01.2016; Amer Chemical Soc
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; TRANSFORMATION; CYCLOADDITION; ANALOGS; 4-(2-CHLORO-5-NITROPHENYL)-1,2,3-THIADIAZOLE; AGENTS; AZIDE; DERIVATIVES

A TBAI-catalyzed reaction between N-tosyl hydrazone and sulfur was developed, leading to 1,2,3-thiadiazoles in moderate to good yields. It represents a facile and practical procedure to access thiadiazole under metal-free conditions. This procedure serves as an improvement for the Hurd–Mori reaction...