Randomized, Single-Blind, Placebo-Controlled Study of Topical Application of the Immune Response Modulator Resiquimod in Healthy Adults - SAUDER, Daniel N; SMITH, Michael H; SENTA-MCMILLIAN, Therese; SORIA, Inmaculada; MENG, Tze-Chiang (Antimicrobial Agents and Chemotherapy, 2003)
Keywords: Adjuvants, Immunologic; Adjuvants, Immunologic - adverse effects; Adjuvants, Immunologic - pharmacokinetics; Adjuvants, Immunologic - pharmacology; Administration, Topical; Adolescent; Adult; Antiviral Agents; Biological and medical sciences; Biomarkers; Cytokines - biosynthesis; Cytokines - blood; Dose-Response Relationship, Drug; Female; Gels; Humans; Imidazoles; Imidazoles - adverse effects; Imidazoles - pharmacokinetics; Imidazoles - pharmacology; Immunohistochemistry; Immunomodulators; Male; Medical sciences; Middle Aged; Pharmacology. Drug treatments; resiquimod; RNA, Messenger - biosynthesis; Single-Blind Method; Skin - chemistry; Skin - metabolism; Human; Immunomodulator; Colloidal gel; Immune response; Healthy subject; Toxicity; Cytokine; Resiquimod; Adult; Pharmacokinetics; Dose activity relation; Percutaneous route