Single and Double Mutations in gyrA but Not in gyrB Are Associated with Low- and High-Level Fluoroquinolone Resistance in Helicobacter pylori

• Published in: Antimicrobial Agents and Chemotherapy Vol. 47; no. 12; pp. 3942 - 3944
• Main Authors: TANKOVIC, Jacques, LASCOLS, Christine, SCULO, Quentin, PETIT, Jean-Claude, SOUSSY, Claude-James
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.12.2003
• Subjects: Anti-Infective Agents; Anti-Infective Agents - pharmacology; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; clinflaxacin; DNA Gyrase; DNA Gyrase - genetics; Drug Resistance, Bacterial; Fluoroquinolones; Fluoroquinolones - pharmacology; France - epidemiology; garenoxacin; Genotype; gyrA gene; Helicobacter Infections - epidemiology; Helicobacter Infections - microbiology; Helicobacter pylori; Helicobacter pylori - drug effects; Humans; Mechanisms of Resistance; Medical sciences; Mutation; Mutation - genetics; Mutation - physiology; Pharmacology. Drug treatments; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; France; Human; Spirillales; Spirillaceae; In vitro; Infection; Resistance; Antibiotic; Fluoroquinolone derivatives; Gene; Helicobacter pylori; Bacteriosis; Bacteria; Mutation; Antibacterial agent; Clinical isolate; Quinolone derivatives

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