Multigenerational and Transgenerational Effects of Environmentally Relevant Concentrations of Endocrine Disruptors in an Estuarine Fish Model

• Published in: Environmental science & technology Vol. 54; no. 21; pp. 13849 - 13860
• Main Authors: DeCourten, Bethany M, Forbes, Joshua P, Roark, Hunter K, Burns, Nathan P, Major, Kaley M, White, J. Wilson, Li, Jie, Mehinto, Alvine C, Connon, Richard E, Brander, Susanne M
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 03.11.2020
• Subjects: abnormal development; Animals; Aquatic organisms; bifenthrin; Contaminants; Deoxyribonucleic acid; DNA; DNA methylation; Ecotoxicology and Public Health; Egg production; Endocrine disruptors; Endocrine Disruptors - toxicity; Environmental effects; Epigenetics; Estuaries; estuarine fish; Estuarine pollution; Ethinyl Estradiol - toxicity; Ethinylestradiol; Exposure; Fishes; Gene expression; Immune response; Immune system; Insecticides; larvae; Larval development; Menidia beryllina; Pollutants; Reproduction; technology; toxic substances; Toxicants; Trenbolone; Water Pollutants, Chemical - toxicity

Many pollutants cause endocrine disruption in aquatic organisms. While studies of the direct effects of toxicants on exposed organisms are commonplace, little is known about the potential for toxicant exposures in a parental (F0) generation to affect unexposed F1 or F2 generations (multigenerational...