Coupling N–H Deprotonation, C–H Activation, and Oxidation: Metal-Free C(sp3)–H Aminations with Unprotected Anilines

An intramolecular oxidative C­(sp3)–H amination from unprotected anilines and C­(sp3)–H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N–H bonds and an activated C­(sp3)–H bond (BDE <...

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Published inJournal of the American Chemical Society Vol. 139; no. 45; pp. 16210 - 16221
Main Authors Evoniuk, Christopher J, Gomes, Gabriel dos Passos, Hill, Sean P, Fujita, Satoshi, Hanson, Kenneth, Alabugin, Igor V
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 15.11.2017
Amer Chemical Soc
Subjects
acidity
amination
aromatic compounds
carbon-hydrogen bond activation
chemical bonding
Chemistry
Chemistry, Multidisciplinary
dimethylformamide
heterocyclic nitrogen compounds
oxidants
oxidation
oxygen
Physical Sciences
Science & Technology
transition elements
AROMATIC-HYDROCARBONS
DENSITY FUNCTIONALS
CHEMICAL-SHIFTS NICS
RADICAL STABILITY
SOMO-HOMO CONVERSION
EFFICIENT SYNTHESIS
CONNECTOR GROUPS
SINGLET OXYGEN
SYNTHETIC APPROACH
INTRAMOLECULAR ADDITION
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Abstract An intramolecular oxidative C­(sp3)–H amination from unprotected anilines and C­(sp3)–H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N–H bonds and an activated C­(sp3)–H bond (BDE < 85 kcal/mol), stems from synergy between basic, radical, and oxidizing species working together to promote a coordinated sequence of deprotonation: H atom transfer and oxidation that forges a new C–N bond. This process is applicable for the synthesis of a wide variety of N-heterocycles, ranging from small molecules to extended aromatics without the need for transition metals or strong oxidants. Computational results reveal the mechanistic details and energy landscape for the sequence of individual steps that comprise this reaction cascade. The importance of base in this process stems from the much greater acidity of transition state and product for the 2c,3e C–N bond formation relative to the reactant. In this scenario, selective deprotonation provides the driving force for the process.
AbstractList An intramolecular oxidative C­(sp3)–H amination from unprotected anilines and C­(sp3)–H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N–H bonds and an activated C­(sp3)–H bond (BDE < 85 kcal/mol), stems from synergy between basic, radical, and oxidizing species working together to promote a coordinated sequence of deprotonation: H atom transfer and oxidation that forges a new C–N bond. This process is applicable for the synthesis of a wide variety of N-heterocycles, ranging from small molecules to extended aromatics without the need for transition metals or strong oxidants. Computational results reveal the mechanistic details and energy landscape for the sequence of individual steps that comprise this reaction cascade. The importance of base in this process stems from the much greater acidity of transition state and product for the 2c,3e C–N bond formation relative to the reactant. In this scenario, selective deprotonation provides the driving force for the process.
An intramolecular oxidative C(sp(3))-H amination from unprotected anilines and C(sp(3))-H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N-H bonds and an activated C(sp(3))-H bond (BDE < 85 kcal/mol), stems from synergy between basic, radical, and oxidizing species working together to promote a coordinated sequence of deprotonation: H atom transfer and oxidation that forges a new C-N bond. This process is applicable for the synthesis of a wide variety of N-heterocycles, ranging from small molecules to extended aromatics without the need for transition metals or strong oxidants. Computational results reveal the mechanistic details and energy landscape for the sequence of individual steps that comprise this reaction cascade. The importance of base in this process stems from the much greater acidity of transition state and product for the 2c,3e C-N bond formation relative to the reactant. In this scenario, selective deprotonation provides the driving force for the process.
An intramolecular oxidative C(sp³)–H amination from unprotected anilines and C(sp³)–H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N–H bonds and an activated C(sp³)–H bond (BDE < 85 kcal/mol), stems from synergy between basic, radical, and oxidizing species working together to promote a coordinated sequence of deprotonation: H atom transfer and oxidation that forges a new C–N bond. This process is applicable for the synthesis of a wide variety of N-heterocycles, ranging from small molecules to extended aromatics without the need for transition metals or strong oxidants. Computational results reveal the mechanistic details and energy landscape for the sequence of individual steps that comprise this reaction cascade. The importance of base in this process stems from the much greater acidity of transition state and product for the 2c,3e C–N bond formation relative to the reactant. In this scenario, selective deprotonation provides the driving force for the process.
An intramolecular oxidative C(sp )-H amination from unprotected anilines and C(sp )-H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N-H bonds and an activated C(sp )-H bond (BDE < 85 kcal/mol), stems from synergy between basic, radical, and oxidizing species working together to promote a coordinated sequence of deprotonation: H atom transfer and oxidation that forges a new C-N bond. This process is applicable for the synthesis of a wide variety of N-heterocycles, ranging from small molecules to extended aromatics without the need for transition metals or strong oxidants. Computational results reveal the mechanistic details and energy landscape for the sequence of individual steps that comprise this reaction cascade. The importance of base in this process stems from the much greater acidity of transition state and product for the 2c,3e C-N bond formation relative to the reactant. In this scenario, selective deprotonation provides the driving force for the process.
An intramolecular oxidative C(sp3)-H amination from unprotected anilines and C(sp3)-H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N-H bonds and an activated C(sp3)-H bond (BDE < 85 kcal/mol), stems from synergy between basic, radical, and oxidizing species working together to promote a coordinated sequence of deprotonation: H atom transfer and oxidation that forges a new C-N bond. This process is applicable for the synthesis of a wide variety of N-heterocycles, ranging from small molecules to extended aromatics without the need for transition metals or strong oxidants. Computational results reveal the mechanistic details and energy landscape for the sequence of individual steps that comprise this reaction cascade. The importance of base in this process stems from the much greater acidity of transition state and product for the 2c,3e C-N bond formation relative to the reactant. In this scenario, selective deprotonation provides the driving force for the process.An intramolecular oxidative C(sp3)-H amination from unprotected anilines and C(sp3)-H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N-H bonds and an activated C(sp3)-H bond (BDE < 85 kcal/mol), stems from synergy between basic, radical, and oxidizing species working together to promote a coordinated sequence of deprotonation: H atom transfer and oxidation that forges a new C-N bond. This process is applicable for the synthesis of a wide variety of N-heterocycles, ranging from small molecules to extended aromatics without the need for transition metals or strong oxidants. Computational results reveal the mechanistic details and energy landscape for the sequence of individual steps that comprise this reaction cascade. The importance of base in this process stems from the much greater acidity of transition state and product for the 2c,3e C-N bond formation relative to the reactant. In this scenario, selective deprotonation provides the driving force for the process.
Author Evoniuk, Christopher J
Alabugin, Igor V
Gomes, Gabriel dos Passos
Hill, Sean P
Fujita, Satoshi
Hanson, Kenneth
AuthorAffiliation Kyushu University
Florida State University
Interdisciplinary Graduate School of Engineering Sciences
AuthorAffiliation_xml – name: Kyushu University
– name: Florida State University
– name: Interdisciplinary Graduate School of Engineering Sciences
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  givenname: Christopher J
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  surname: Evoniuk
  fullname: Evoniuk, Christopher J
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  givenname: Gabriel dos Passos
  orcidid: 0000-0002-8235-5969
  surname: Gomes
  fullname: Gomes, Gabriel dos Passos
  organization: Florida State University
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  givenname: Sean P
  surname: Hill
  fullname: Hill, Sean P
  organization: Florida State University
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  givenname: Satoshi
  surname: Fujita
  fullname: Fujita, Satoshi
  organization: Kyushu University
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  givenname: Kenneth
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  surname: Alabugin
  fullname: Alabugin, Igor V
  email: alabugin@chem.fsu.edu
  organization: Florida State University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/29037029$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1021/ar700111a
10.1021/jacs.5b03118
10.1002/cber.19090420377
10.1038/nchem.1625
10.1016/j.chempr.2017.04.007
10.1021/jacs.7b07113
10.1002/1522-2675(200201)85:1<1::AID-HLCA1>3.0.CO;2-C
10.1021/jo500071u
10.1002/chem.200900990
10.1021/jacs.6b03282
10.1002/chem.201304307
10.1021/ol047876l
10.1039/C6OB02684B
10.1139/v67-504
10.1002/anie.201007654
10.1038/nchem.2031
10.1021/acs.orglett.6b02914
10.1021/jacs.6b08540
10.1063/1.3382344
10.1002/anie.201502332
10.1039/C3CS60318K
10.1021/jo701641b
10.1007/s00214-007-0310-x
10.1007/128_2008_46
10.1021/jp3101927
10.1021/acs.joc.7b00549
10.1021/ja404279f
10.1021/ja072521t
10.1021/ja411662a
10.1002/chem.200801810
10.1021/jacs.5b05377
10.1021/jacs.5b12642
10.1246/cl.161122
10.1038/nature06485
10.1002/anie.201402443
10.1002/chem.201603336
10.1021/acs.chemrev.6b00644
10.1021/jo3005952
10.1021/cr030088+
10.1021/j150571a003
10.1002/anie.201209479
10.1002/anie.201502436
10.1021/jo101838a
10.1039/b905820f
10.1021/jo051746o
10.1002/chem.200900281
10.1021/jp3064245
10.1063/1.478522
10.1039/c0cs00095g
10.1039/jr9510003113
10.1126/science.aac9895
10.1021/jacs.6b13032
10.1039/C3SC52315B
10.1021/ja802491q
10.1021/jo00075a041
10.1039/C6OB00423G
10.1002/cber.188301601120
10.1002/chem.201502777
10.1021/jo1000753
10.1002/ejoc.201501520
10.1246/cl.2012.215
10.1071/CH9641138
10.1002/chem.201200888
10.1002/anie.201606330
10.1016/j.tet.2009.06.109
10.1002/poc.1054
10.1021/ja973366t
10.1021/ja9054959
10.1039/C6SC02231F
10.1002/anie.201209591
10.1038/nchem.2018
10.1021/ja00360a039
10.1039/C5RA07188G
10.1021/ja106852n
10.1126/science.aac8555
10.1002/anie.201511847
10.1002/anie.201400557
10.1021/jp810292n
10.1039/C7CC03898D
10.1021/jp072456+
10.1016/j.chempr.2017.05.018
10.1039/c3cc46340k
10.1055/s-0035-1561642
10.1002/anie.201601930
10.1016/j.tet.2009.10.086
10.1021/ja8028069
10.1021/ja402647m
10.1021/jacs.5b01197
10.1002/poc.3744
10.1021/cr60221a004
10.1021/ja807129e
10.1021/jp501256f
10.1002/chem.201604602
10.1021/acs.joc.6b01395
10.1002/anie.201208066
10.1351/pac200476030577
10.1038/ncomms5707
10.1039/c3sc51420j
10.1016/S0040-4039(01)02192-X
10.1021/jo501179t
10.1021/acs.chemmater.7b01318
10.1021/jacs.6b13031
10.1021/ar200318q
10.1039/C6CC03106D
10.1039/c7cc03898d
10.1039/c6sc02231f
10.1039/c3cs60318k
10.1039/c5ra07188g
10.1039/c6ob00423g
10.1021/Ja8028069
10.1039/c3sc52315b
10.1039/c6ob02684b
10.1038/NCHEM.1625
10.1039/c6cc03106d
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Issue 45
Keywords AROMATIC-HYDROCARBONS
DENSITY FUNCTIONALS
CHEMICAL-SHIFTS NICS
RADICAL STABILITY
SOMO-HOMO CONVERSION
EFFICIENT SYNTHESIS
CONNECTOR GROUPS
SINGLET OXYGEN
SYNTHETIC APPROACH
INTRAMOLECULAR ADDITION
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References ref17/cit17b
ref17/cit17c
ref17/cit17d
ref3/cit3
ref1/cit1e
ref1/cit1d
ref1/cit1g
ref1/cit1f
ref17/cit17a
ref16/cit16
ref23/cit23
ref1/cit1a
ref1/cit1c
ref1/cit1b
ref20/cit20
ref5/cit5b
ref5/cit5c
ref5/cit5a
ref35/cit35
ref36/cit36a
ref36/cit36b
ref42/cit42
ref13/cit13
ref19/cit19a
ref38/cit38
ref5/cit5d
ref19/cit19b
ref10/cit10d
ref29/cit29c
ref29/cit29b
ref29/cit29a
ref8/cit8a
ref10/cit10a
ref8/cit8c
ref10/cit10b
ref8/cit8b
ref10/cit10c
ref29/cit29d
ref32/cit32
ref49/cit49a
ref49/cit49b
ref39/cit39a
ref49/cit49c
ref39/cit39b
ref28/cit28
ref49/cit49d
ref41/cit41b
ref49/cit49e
ref41/cit41a
ref4/cit4a
ref4/cit4b
ref4/cit4c
ref12/cit12
ref50/cit50f
ref50/cit50g
ref22/cit22
ref40/cit40b
ref50/cit50d
ref40/cit40c
ref50/cit50e
ref48/cit48a
ref50/cit50b
ref33/cit33
ref50/cit50c
ref50/cit50a
ref4/cit4d
ref10/cit10a1
ref48/cit48e
ref48/cit48d
ref48/cit48c
ref48/cit48b
ref40/cit40a
ref48/cit48g
ref48/cit48f
ref27/cit27
Lu H.-J. (ref5/cit5e) 2016; 7
ref2/cit2c
ref2/cit2b
ref2/cit2a
ref34/cit34
Goswami M. (ref5/cit5f) 2015; 137
ref21/cit21
ref11/cit11b
ref46/cit46
ref11/cit11a
ref45/cit45c
ref45/cit45b
ref45/cit45a
ref9/cit9c
ref9/cit9b
ref9/cit9a
ref25/cit25
ref14/cit14
ref9/cit9e
ref9/cit9d
ref45/cit45d
ref44/cit44a
ref26/cit26
ref24/cit24b
Legault C. Y. (ref31/cit31) 2009
ref15/cit15
ref24/cit24a
Lu H.-J. (ref5/cit5g) 2014; 53
ref30/cit30
ref6/cit6a
ref47/cit47
ref6/cit6b
ref6/cit6c
ref44/cit44b
ref7/cit7
(000415785900035.1) 2017
Zatolochnaya, OV (WOS:000341371100004) 2014; 6
Bunz, UHF (WOS:000316915500005) 2013; 52
Drapeau, MP (WOS:000360312800034) 2015; 54
Banerjee, S (WOS:000402498500023) 2017; 139
Choi, GJ (WOS:000358896600008) 2015; 137
Nguyen, KMH (WOS:000370337700024) 2016; 2016
Stanger, A (WOS:000275884400015) 2010; 75
Zhu, XQ (WOS:000304129400029) 2012; 77
Goswami, M (WOS:000353931500039) 2015; 137
Yu, A (WOS:000249838100042) 2007; 111
Brandi, P (WOS:000243647800014) 2006; 19
Syroeshkin, MA (WOS:000409339500016) 2017; 30
Yang, H (WOS:000393599700011) 2017; 23
Menon, AS (WOS:000311872200019) 2012; 116
BORDWELL, FG (WOS:A1993MF51600041) 1993; 58
Takahashi, I (WOS:000396062600018) 2017; 46
Thansandote, P (WOS:000267278900001) 2009; 15
Jeffrey, JL (WOS:000314998500009) 2013; 52
Rice, GT (WOS:000269379400030) 2009; 131
Lu, HJ (WOS:000391453200008) 2016; 7
BRESLOW, R (WOS:A1983RP96900039) 1983; 105
Louillat, ML (WOS:000329927100010) 2014; 43
Zhang, G (WOS:000384806700039) 2016; 22
Zhao, Y (WOS:000253323800001) 2008; 41
Intrieri, D (WOS:000307387300003) 2012; 18
Rahalkar, A. (000415785900035.77) 1000
Tverskoy, O (WOS:000289264200040) 2011; 50
Löffler, K (WOS:000201158100075) 1909; 42
Endres, AH (WOS:000370582900013) 2016; 138
Jeffrey, JL (WOS:000325409500001) 2013; 4
Liu, WB (WOS:000402498500022) 2017; 139
Fogel, Y (WOS:000249693800023) 2007; 129
Hosokawa, T (WOS:000419082100023) 2017; 139
Chen, YY (WOS:000355703700090) 2015; 5
Peterson, PW (WOS:000389623800021) 2016; 138
Barham, JP (WOS:000373133000012) 2016; 55
Davies, HML (WOS:000252554100035) 2008; 451
Zhao, Y (WOS:000256308800019) 2008; 120
Legault, C. Y. (000415785900035.55) 2009
Zhou, SZ (WOS:000328954200004) 2014; 5
Emery, KJ (WOS:000394955200021) 2017; 15
Wang, HQ (WOS:000387303200059) 2016; 18
Studer, A (WOS:000341373500009) 2014; 6
Stanger, A (WOS:000235101100004) 2006; 71
Mohamed, RK (WOS:000384713100065) 2016; 55
Baciocchi, E (WOS:000225548600038) 2004; 6
Caronna, T (WOS:000173955600001) 2002; 85
Nguyen, TM (WOS:000337095000031) 2014; 53
BOWEN, EJ (WOS:A1959WK47900003) 1959; 63
WOLFF, ME (WOS:A19638640A00005) 1963; 63
Lovinger, AJ (WOS:000071624500004) 1998; 120
Wang, ZL (WOS:000411278200017) 2017; 53
Marenich, AV (WOS:000265687500026) 2009; 113
Jun, CH (WOS:000221367800013) 2004; 76
Collet, F (WOS:000269081900001) 2009
Bisai, A (WOS:000256550600028) 2008; 130
GRIMME S (WOS:000415785900035.40) 2010; 132
Wang, XB (WOS:000408621400008) 2017; 2
Bunz, UHF (WOS:000268286200001) 2009; 15
Doni, E (WOS:000314998500019) 2013; 52
Waghray, D (WOS:000368280400043) 2015; 21
Gryn'ova, G (WOS:000319404900009) 2013; 5
Chen, ZF (WOS:000232755200014) 2005; 105
Reeves, JT (WOS:000317872800020) 2013; 135
Pal, R (WOS:000285081100046) 2010; 75
Ankner, T (WOS:000272918300014) 2009; 65
Chen, YY (WOS:000326460000025) 2013; 49
Barham, JP (WOS:000378193300032) 2016; 138
Gruver, JM (WOS:000282304000042) 2010; 132
Gu, PY (WOS:000402498000004) 2017; 29
Shi, F (WOS:000280909300005) 2010; 292
Wasa, M (WOS:000260301700019) 2008; 130
Umeda, R (WOS:000303273800004) 2012; 41
Gershoni-Poranne, R (WOS:000335197000023) 2014; 20
BRAUDE, EA (WOS:A1951UB66700067) 1951
BADGER, GM (WOS:A19646107A00002) 1964; 17
Adamo, C (WOS:000079419000010) 1999; 110
Collet, F (WOS:000288609400008) 2011; 40
Frisch, M. J. (000415785900035.36) 2009
Morris, M (WOS:000312519800021) 2012; 116
Hauser, A (WOS:000381114000022) 2016; 27
Park, Y (WOS:000405642800019) 2017; 117
Upadhyay, GM (WOS:000382713800046) 2016; 81
Romero, NA (WOS:000361357700046) 2015; 349
Mori, K (WOS:000355314100029) 2015; 54
Yang, MY (WOS:000341078900005) 2014; 5
Chen, JH (WOS:000374878400010) 2016; 14
Wang, WJ (WOS:000342121100007) 2014; 79
Van Hoomissen, DJ (WOS:000402851000022) 2017; 82
Papin, C (WOS:000262301900008) 2009; 15
Haddach, AA (WOS:000173262000014) 2002; 43
Gryn'ova, G (WOS:000326125200026) 2013; 135
Baciocchi, E (WOS:000251313600020) 2007; 72
Opstad, CL (WOS:000269340000039) 2009; 65
Roizen, JL (WOS:000305321100013) 2012; 45
Fujikawa, T (WOS:000357062000043) 2015; 137
Franchi, P (WOS:000330598600024) 2014; 136
Alabugin, IV (WOS:000408621400003) 2017; 2
Lu, HJ (WOS:000338023000037) 2014; 53
Dewanji, A (WOS:000377921300031) 2016; 55
Chen, K (WOS:000256550600038) 2008; 130
Hofmann, A. W. (000415785900035.48) 1883; 16
Morris, M (WOS:000334731100015) 2014; 118
Murphy, JA (WOS:000335490700001) 2014; 79
HEUMANN, WR (WOS:A1967A405700016) 1967; 45
Evoniuk, CJ (WOS:000377083300017) 2016; 52
Jeffrey, JL (WOS:000361707000046) 2015; 349
References_xml – ident: ref24/cit24b
  doi: 10.1021/ar700111a
– ident: ref48/cit48e
  doi: 10.1021/jacs.5b03118
– ident: ref4/cit4b
  doi: 10.1002/cber.19090420377
– ident: ref9/cit9a
  doi: 10.1038/nchem.1625
– ident: ref1/cit1g
  doi: 10.1016/j.chempr.2017.04.007
– ident: ref48/cit48g
  doi: 10.1021/jacs.7b07113
– ident: ref49/cit49d
  doi: 10.1002/1522-2675(200201)85:1<1::AID-HLCA1>3.0.CO;2-C
– ident: ref44/cit44a
  doi: 10.1021/jo500071u
– ident: ref50/cit50c
  doi: 10.1002/chem.200900990
– ident: ref17/cit17a
  doi: 10.1021/jacs.6b03282
– ident: ref29/cit29d
  doi: 10.1002/chem.201304307
– ident: ref45/cit45b
  doi: 10.1021/ol047876l
– ident: ref19/cit19a
  doi: 10.1039/C6OB02684B
– ident: ref34/cit34
  doi: 10.1139/v67-504
– ident: ref50/cit50a
  doi: 10.1002/anie.201007654
– ident: ref20/cit20
  doi: 10.1038/nchem.2031
– ident: ref14/cit14
  doi: 10.1021/acs.orglett.6b02914
– ident: ref38/cit38
  doi: 10.1021/jacs.6b08540
– ident: ref26/cit26
  doi: 10.1063/1.3382344
– ident: ref23/cit23
  doi: 10.1002/anie.201502332
– ident: ref1/cit1b
  doi: 10.1039/C3CS60318K
– ident: ref45/cit45a
  doi: 10.1021/jo701641b
– ident: ref24/cit24a
  doi: 10.1007/s00214-007-0310-x
– ident: ref2/cit2c
  doi: 10.1007/128_2008_46
– ident: ref9/cit9d
  doi: 10.1021/jp3101927
– ident: ref12/cit12
  doi: 10.1021/acs.joc.7b00549
– ident: ref9/cit9b
  doi: 10.1021/ja404279f
– ident: ref50/cit50d
  doi: 10.1021/ja072521t
– ident: ref9/cit9c
  doi: 10.1021/ja411662a
– ident: ref40/cit40c
  doi: 10.1002/chem.200801810
– ident: ref10/cit10b
  doi: 10.1021/jacs.5b05377
– ident: ref50/cit50f
  doi: 10.1021/jacs.5b12642
– ident: ref49/cit49b
  doi: 10.1246/cl.161122
– ident: ref5/cit5d
  doi: 10.1038/nature06485
– ident: ref10/cit10d
  doi: 10.1002/anie.201402443
– ident: ref32/cit32
– ident: ref46/cit46
  doi: 10.1002/chem.201603336
– ident: ref1/cit1a
  doi: 10.1021/acs.chemrev.6b00644
– ident: ref15/cit15
  doi: 10.1021/jo3005952
– ident: ref28/cit28
  doi: 10.1021/cr030088+
– ident: ref47/cit47
  doi: 10.1021/j150571a003
– ident: ref50/cit50b
  doi: 10.1002/anie.201209479
– ident: ref48/cit48b
  doi: 10.1002/anie.201502436
– ident: ref41/cit41a
  doi: 10.1021/jo101838a
– ident: ref1/cit1e
  doi: 10.1039/b905820f
– ident: ref29/cit29b
  doi: 10.1021/jo051746o
– ident: ref1/cit1f
  doi: 10.1002/chem.200900281
– ident: ref41/cit41b
  doi: 10.1021/jp3064245
– ident: ref27/cit27
  doi: 10.1063/1.478522
– ident: ref1/cit1c
  doi: 10.1039/c0cs00095g
– ident: ref49/cit49e
  doi: 10.1039/jr9510003113
– ident: ref10/cit10c
  doi: 10.1126/science.aac9895
– ident: ref36/cit36b
  doi: 10.1021/jacs.6b13032
– ident: ref44/cit44b
  doi: 10.1039/C3SC52315B
– ident: ref4/cit4d
  doi: 10.1021/ja802491q
– ident: ref11/cit11a
  doi: 10.1021/jo00075a041
– ident: ref17/cit17d
  doi: 10.1039/C6OB00423G
– ident: ref4/cit4a
  doi: 10.1002/cber.188301601120
– ident: ref48/cit48f
  doi: 10.1002/chem.201502777
– ident: ref29/cit29c
  doi: 10.1021/jo1000753
– ident: ref29/cit29a
– ident: ref3/cit3
  doi: 10.1002/ejoc.201501520
– ident: ref49/cit49a
  doi: 10.1246/cl.2012.215
– ident: ref49/cit49c
  doi: 10.1071/CH9641138
– ident: ref5/cit5b
  doi: 10.1002/chem.201200888
– ident: ref48/cit48a
  doi: 10.1002/anie.201606330
– ident: ref10/cit10a
  doi: 10.1016/j.chempr.2017.04.007
– ident: ref33/cit33
– ident: ref21/cit21
  doi: 10.1016/j.tet.2009.06.109
– ident: ref13/cit13
  doi: 10.1002/poc.1054
– ident: ref48/cit48d
  doi: 10.1021/ja973366t
– ident: ref6/cit6b
  doi: 10.1021/ja9054959
– volume: 7
  start-page: 6934
  year: 2016
  ident: ref5/cit5e
  publication-title: Chem. Sci
  doi: 10.1039/C6SC02231F
– ident: ref8/cit8c
  doi: 10.1002/anie.201209591
– ident: ref2/cit2a
  doi: 10.1038/nchem.2018
– ident: ref5/cit5a
  doi: 10.1021/ja00360a039
– ident: ref22/cit22
  doi: 10.1039/C5RA07188G
– ident: ref8/cit8b
  doi: 10.1021/ja106852n
– ident: ref39/cit39b
  doi: 10.1126/science.aac8555
– ident: ref19/cit19b
  doi: 10.1002/anie.201511847
– volume: 53
  start-page: 7028
  year: 2014
  ident: ref5/cit5g
  publication-title: Angew. Chem. Int. Ed.
  doi: 10.1002/anie.201400557
– ident: ref25/cit25
  doi: 10.1021/jp810292n
– ident: ref50/cit50e
  doi: 10.1039/C7CC03898D
– ident: ref11/cit11b
  doi: 10.1021/jp072456+
– ident: ref10/cit10a1
  doi: 10.1016/j.chempr.2017.05.018
– ident: ref17/cit17c
  doi: 10.1039/c3cc46340k
– ident: ref45/cit45d
  doi: 10.1055/s-0035-1561642
– ident: ref39/cit39a
  doi: 10.1002/anie.201601930
– ident: ref40/cit40b
  doi: 10.1016/j.tet.2009.10.086
– ident: ref8/cit8a
  doi: 10.1021/ja8028069
– ident: ref35/cit35
  doi: 10.1021/ja402647m
– volume: 137
  start-page: 5468
  year: 2015
  ident: ref5/cit5f
  publication-title: J. Am. Chem. Soc.
  doi: 10.1021/jacs.5b01197
– ident: ref42/cit42
  doi: 10.1002/poc.3744
– ident: ref4/cit4c
  doi: 10.1021/cr60221a004
– ident: ref6/cit6a
  doi: 10.1021/ja807129e
– ident: ref9/cit9e
  doi: 10.1021/jp501256f
– ident: ref16/cit16
  doi: 10.1002/chem.201604602
– ident: ref48/cit48c
  doi: 10.1021/acs.joc.6b01395
– ident: ref40/cit40a
  doi: 10.1002/anie.201208066
– ident: ref2/cit2b
  doi: 10.1351/pac200476030577
– ident: ref6/cit6c
  doi: 10.1038/ncomms5707
– volume-title: CYLview
  year: 2009
  ident: ref31/cit31
– ident: ref1/cit1d
  doi: 10.1039/c3sc51420j
– ident: ref45/cit45c
  doi: 10.1016/S0040-4039(01)02192-X
– ident: ref17/cit17b
  doi: 10.1021/jo501179t
– ident: ref50/cit50g
  doi: 10.1021/acs.chemmater.7b01318
– ident: ref36/cit36a
  doi: 10.1021/jacs.6b13031
– ident: ref5/cit5c
  doi: 10.1021/ar200318q
– ident: ref7/cit7
  doi: 10.1039/C6CC03106D
– ident: ref30/cit30
– volume: 27
  start-page: 1870
  year: 2016
  ident: WOS:000381114000022
  article-title: Preparation of Aldehydes by Oxidation of Benzylic Amines with Selectfluor (F-TEDA-BF4)
  publication-title: SYNLETT
  doi: 10.1055/s-0035-1561642
– volume: 55
  start-page: 4492
  year: 2016
  ident: WOS:000373133000012
  article-title: Double Deprotonation of Pyridinols Generates Potent Organic Electron-Donor Initiators for Haloarene-Arene Coupling
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201511847
– volume: 130
  start-page: 7247
  year: 2008
  ident: WOS:000256550600038
  article-title: 1,3-diol synthesis via controlled, radical-mediated C-H functionalization
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/ja802491q
– volume: 49
  start-page: 10974
  year: 2013
  ident: WOS:000326460000025
  article-title: Efficient cyclization of tertiary amines and alkenes promoted by KOt-Bu-DMF
  publication-title: CHEMICAL COMMUNICATIONS
  doi: 10.1039/c3cc46340k
– volume: 72
  start-page: 9582
  year: 2007
  ident: WOS:000251313600020
  article-title: Singlet oxygen promoted carbon-heteroatom bond cleavage in dibenzyl sulfides and tertiary dibenzylamines. Structural effects and the role of exciplexes
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/jo701641b
– volume: 292
  start-page: 123
  year: 2010
  ident: WOS:000280909300005
  article-title: Remote C-H Activation via Through-Space Palladium and Rhodium Migrations
  publication-title: C-H ACTIVATION
  doi: 10.1007/128_2008_46
– volume: 55
  start-page: 12054
  year: 2016
  ident: WOS:000384713100065
  article-title: Alkynes as Linchpins for the Additive Annulation of Biphenyls: Convergent Construction of Functionalized Fused Helicenes
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201606330
– year: 2009
  ident: 000415785900035.36
  publication-title: Gaussian 09, revision E.01
– volume: 79
  start-page: 8557
  year: 2014
  ident: WOS:000342121100007
  article-title: Direct Inter- and Intramolecular Addition of Amides to Arylalkenes Promoted by KOt-Bu/DMF
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/jo501179t
– volume: 41
  start-page: 157
  year: 2008
  ident: WOS:000253323800001
  article-title: Density functionals with broad applicability in chemistry
  publication-title: ACCOUNTS OF CHEMICAL RESEARCH
  doi: 10.1021/ar700111a
– volume: 118
  start-page: 2810
  year: 2014
  ident: WOS:000334731100015
  article-title: Effect of Protonation State and Interposed Connector Groups on Bond Dissociation Enthalpies of Alcohols and Related Systems
  publication-title: JOURNAL OF PHYSICAL CHEMISTRY A
  doi: 10.1021/jp501256f
– volume: 137
  start-page: 5468
  year: 2015
  ident: WOS:000353931500039
  article-title: Characterization of Porphyrin-Co(III)-'Nitrene Radical' Species Relevant in Catalytic Nitrene Transfer Reactions
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.5b01197
– volume: 53
  start-page: 7772
  year: 2017
  ident: WOS:000411278200017
  article-title: A large pyrene-fused N-heteroacene: fifteen aromatic six- membered rings annulated in one row
  publication-title: CHEMICAL COMMUNICATIONS
  doi: 10.1039/c7cc03898d
– volume: 54
  start-page: 6847
  year: 2015
  ident: WOS:000355314100029
  article-title: One-Step Synthesis of [16]Helicene
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201502436
– volume: 7
  start-page: 6934
  year: 2016
  ident: WOS:000391453200008
  article-title: Intramolecular 1,5-C(sp3)-H radical amination via Co(II)-based metalloradical catalysis for five-membered cyclic sulfamides
  publication-title: CHEMICAL SCIENCE
  doi: 10.1039/c6sc02231f
– volume: 43
  start-page: 901
  year: 2014
  ident: WOS:000329927100010
  article-title: Oxidative C-H amination reactions
  publication-title: CHEMICAL SOCIETY REVIEWS
  doi: 10.1039/c3cs60318k
– volume: 129
  start-page: 11743
  year: 2007
  ident: WOS:000249693800023
  article-title: Electron-deficient N-heteroaromatic linkers for the elaboration of large, soluble polycyclic aromatic hydrocarbons and their use in the synthesis of some very large transition metal complexes
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/ja072521t
– volume: 53
  start-page: 7028
  year: 2014
  ident: WOS:000338023000037
  article-title: Chemoselective Amination of Propargylic C(sp3)-H Bonds by Cobalt(II)-Based Metalloradical Catalysis
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201400557
– volume: 135
  start-page: 15392
  year: 2013
  ident: WOS:000326125200026
  article-title: Origin and Scope of Long-Range Stabilizing Interactions and Associated SOMO-HOMO Conversion in Distonic Radical Anions
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/ja404279f
– volume: 113
  start-page: 6378
  year: 2009
  ident: WOS:000265687500026
  article-title: Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions
  publication-title: JOURNAL OF PHYSICAL CHEMISTRY B
  doi: 10.1021/jp810292n
– volume: 5
  start-page: 48046
  year: 2015
  ident: WOS:000355703700090
  article-title: KOt-Bu/DMF promoted intramolecular cyclization of 1,1′-biphenyl aldehydes and ketones: an efficient synthesis of phenanthrenes
  publication-title: RSC ADVANCES
  doi: 10.1039/c5ra07188g
– volume: 14
  start-page: 4071
  year: 2016
  ident: WOS:000374878400010
  article-title: Intramolecular addition of diarylmethanols to imines promoted by KOt-Bu/DMF: a new synthetic approach to indole derivatives
  publication-title: ORGANIC & BIOMOLECULAR CHEMISTRY
  doi: 10.1039/c6ob00423g
– start-page: 5061
  year: 2009
  ident: WOS:000269081900001
  article-title: Catalytic C-H amination: recent progress and future directions
  publication-title: CHEMICAL COMMUNICATIONS
  doi: 10.1039/b905820f
– volume: 81
  start-page: 7751
  year: 2016
  ident: WOS:000382713800046
  article-title: Synthesis and Photophysical Properties of Aza[n]helicenes
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/acs.joc.6b01395
– volume: 110
  start-page: 6158
  year: 1999
  ident: WOS:000079419000010
  article-title: Toward reliable density functional methods without adjustable parameters: The PBE0 model
  publication-title: JOURNAL OF CHEMICAL PHYSICS
– volume: 2
  start-page: 803
  year: 2017
  ident: WOS:000408621400008
  article-title: A Radical Cascade Enabling Collective Syntheses of Natural Products
  publication-title: CHEM
  doi: 10.1016/j.chempr.2017.04.007
– volume: 71
  start-page: 883
  year: 2006
  ident: WOS:000235101100004
  article-title: Nucleus-independent chemical shifts (NICS): Distance dependence and revised criteria for aromaticity and antiaromaticity
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/jo051746o
– volume: 63
  start-page: 4
  year: 1959
  ident: WOS:A1959WK47900003
  article-title: THE EFFECT OF TEMPERATURE ON FLUORESCENCE OF SOLUTIONS
  publication-title: JOURNAL OF PHYSICAL CHEMISTRY
– volume: 50
  start-page: 3557
  year: 2011
  ident: WOS:000289264200040
  article-title: An Efficient Synthesis of Tetraazapentacenes
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201007654
– volume: 85
  start-page: 1
  year: 2002
  ident: WOS:000173955600001
  article-title: Approaches to the azahelicene system: Synthesis and spectroscopic characterization of some diazapentahelicenes
  publication-title: HELVETICA CHIMICA ACTA
– volume: 65
  start-page: 10856
  year: 2009
  ident: WOS:000272918300014
  article-title: SmI2/H2O/amine promoted reductive cleavage of benzyl-heteroatom bonds: optimization and mechanism
  publication-title: TETRAHEDRON
  doi: 10.1016/j.tet.2009.10.086
– volume: 52
  start-page: 3810
  year: 2013
  ident: WOS:000316915500005
  article-title: Large N-Heteroacenes: New Tricks for Very Old Dogs?
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201209479
– volume: 130
  start-page: 14058
  year: 2008
  ident: WOS:000260301700019
  article-title: Synthesis of β-, γ-, and δ-Lactams via Pd(II)-Catalyzed C-H Activation Reactions
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/ja807129e
– volume: 40
  start-page: 1926
  year: 2011
  ident: WOS:000288609400008
  article-title: Catalytic C-H amination: the stereoselectivity issue
  publication-title: CHEMICAL SOCIETY REVIEWS
  doi: 10.1039/c0cs00095g
– volume: 117
  start-page: 9247
  year: 2017
  ident: WOS:000405642800019
  article-title: Transition Metal-Catalyzed C-H Amination: Scope, Mechanism, and Applications
  publication-title: CHEMICAL REVIEWS
  doi: 10.1021/acs.chemrev.6b00644
– volume: 29
  start-page: 4172
  year: 2017
  ident: WOS:000402498000004
  article-title: Synthesis, Full Characterization, and Field Effect Transistor Behavior of a Stable Pyrene-Fused N-Heteroacene with Twelve Linearly Annulated Six-Membered Rings
  publication-title: CHEMISTRY OF MATERIALS
  doi: 10.1021/acs.chemmater.7b01318
– volume: 65
  start-page: 7616
  year: 2009
  ident: WOS:000269340000039
  article-title: Formation of DMSO and DMF radicals with minute amounts of base
  publication-title: TETRAHEDRON
  doi: 10.1016/j.tet.2009.06.109
– volume: 63
  start-page: 55
  year: 1963
  ident: WOS:A19638640A00005
  article-title: CYCLIZATION OF N-HALOGENATED AMINES (HOFMANN-LOFFLER REACTION
  publication-title: CHEMICAL REVIEWS
– volume: 136
  start-page: 1250
  year: 2014
  ident: WOS:000330598600024
  article-title: SOMO-HOMO Conversion in Distonic Radical Anions: An Experimental Test in Solution by EPR Radical Equilibration Technique
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/ja411662a
– volume: 53
  start-page: 6198
  year: 2014
  ident: WOS:000337095000031
  article-title: anti-Markovnikov Hydroamination of Alkenes Catalyzed by a Two-Component Organic Photoredox System: Direct Access to Phenethylamine Derivatives
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201402443
– volume: 19
  start-page: 552
  year: 2006
  ident: WOS:000243647800014
  article-title: Stereoelectronic effects in radical processes
  publication-title: JOURNAL OF PHYSICAL ORGANIC CHEMISTRY
  doi: 10.1002/poc.1054
– volume: 18
  start-page: 10487
  year: 2012
  ident: WOS:000307387300003
  article-title: [Ru(TPP)CO]-Catalysed Intramolecular Benzylic C?H Bond Amination, Affording Phenanthridine and Dihydrophenanthridine Derivatives
  publication-title: CHEMISTRY-A EUROPEAN JOURNAL
  doi: 10.1002/chem.201200888
– volume: 120
  start-page: 215
  year: 2008
  ident: WOS:000256308800019
  article-title: The M06 suite of density functionals for main group thermochemistry, thermochemical kinetics, noncovalent interactions, excited states, and transition elements: two new functionals and systematic testing of four M06-class functionals and 12 other functionals
  publication-title: THEORETICAL CHEMISTRY ACCOUNTS
  doi: 10.1007/s00214-007-0310-x
– volume: 15
  start-page: 5874
  year: 2009
  ident: WOS:000267278900001
  article-title: Construction of Nitrogen-Containing Heterocycles by C-H Bond Functionalization
  publication-title: CHEMISTRY-A EUROPEAN JOURNAL
  doi: 10.1002/chem.200900281
– volume: 130
  start-page: 7222
  year: 2008
  ident: WOS:000256550600028
  article-title: Unified strategy for the synthesis of the "Miscellaneous" lycopodium alkaloids:: Total synthesis of (±)-lyconadin A
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/Ja8028069
– volume: 139
  start-page: 6880
  year: 2017
  ident: WOS:000402498500023
  article-title: Ionic and Neutral Mechanisms for C-H Bond Silylation of Aromatic Heterocycles Catalyzed by Potassium tert-Butoxide
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.6b13032
– volume: 4
  start-page: 4092
  year: 2013
  ident: WOS:000325409500001
  article-title: Intramolecular C(sp3)-H amination
  publication-title: CHEMICAL SCIENCE
  doi: 10.1039/c3sc51420j
– volume: 5
  start-page: 476
  year: 2014
  ident: WOS:000328954200004
  article-title: Organic super-electron-donors: initiators in transition metal-free haloarene-arene coupling
  publication-title: CHEMICAL SCIENCE
  doi: 10.1039/c3sc52315b
– volume: 137
  start-page: 7763
  year: 2015
  ident: WOS:000357062000043
  article-title: Synthesis, Structures, and Properties of π-Extended Double Helicene: A Combination of Planar and Nonplanar π-Systems
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.5b03118
– volume: 6
  start-page: 765
  year: 2014
  ident: WOS:000341373500009
  article-title: The electron is a catalyst
  publication-title: NATURE CHEMISTRY
  doi: 10.1038/nchem.2031
– volume: 349
  start-page: 1532
  year: 2015
  ident: WOS:000361707000046
  article-title: O-H hydrogen bonding promotes H-atom transfer from α C-H bonds for C-alkylation of alcohols
  publication-title: SCIENCE
  doi: 10.1126/science.aac8555
– volume: 17
  start-page: 1138
  year: 1964
  ident: WOS:A19646107A00002
  article-title: FORMATION OF AROMATIC HYDROCARBONS AT HIGH TEMPERATURES .22. PYROLYSIS OF PHENANTHRENE
  publication-title: AUSTRALIAN JOURNAL OF CHEMISTRY
– volume: 20
  start-page: 5673
  year: 2014
  ident: WOS:000335197000023
  article-title: The NICS- XY- Scan: Identification of Local and Global Ring Currents in Multi- Ring Systems
  publication-title: CHEMISTRY-A EUROPEAN JOURNAL
  doi: 10.1002/chem.201304307
– volume: 18
  start-page: 5680
  year: 2016
  ident: WOS:000387303200059
  article-title: KOtBu-Promoted Oxidation of (Hetero)benzylic Csp3-H to Ketones with Molecular Oxygen
  publication-title: ORGANIC LETTERS
  doi: 10.1021/acs.orglett.6b02914
– volume: 105
  start-page: 6728
  year: 1983
  ident: WOS:A1983RP96900039
  article-title: INTRAMOLECULAR NITRENE C-H INSERTIONS MEDIATED BY TRANSITION-METAL COMPLEXES AS NITROGEN ANALOGS OF CYTOCHROME-P-450 REACTIONS
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
– volume: 45
  start-page: 911
  year: 2012
  ident: WOS:000305321100013
  article-title: Metal-Catalyzed Nitrogen-Atom Transfer Methods for the Oxidation of Aliphatic C-H Bonds
  publication-title: ACCOUNTS OF CHEMICAL RESEARCH
  doi: 10.1021/ar200318q
– volume: 2016
  start-page: 1025
  year: 2016
  ident: WOS:000370337700024
  article-title: Catalytic Oxidative Coupling of Primary Amines under Air: A Flexible Route to Benzimidazole Derivatives
  publication-title: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1002/ejoc.201501520
– volume: 132
  start-page: 13212
  year: 2010
  ident: WOS:000282304000042
  article-title: Experimental Characterization and Computational Study of Unique C,N-Chelated Lithium Dianions
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/ja106852n
– volume: 21
  start-page: 18791
  year: 2015
  ident: WOS:000368280400043
  article-title: Diastereoselective Strategies towards Thia[n]helicenes
  publication-title: CHEMISTRY-A EUROPEAN JOURNAL
  doi: 10.1002/chem.201502777
– volume: 55
  start-page: 6749
  year: 2016
  ident: WOS:000377921300031
  article-title: Radical Hydrodeiodination of Aryl, Alkenyl, Alkynyl, and Alkyl Iodides with an Alcoholate as Organic Chain Reductant through Electron Catalysis
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201601930
– volume: 116
  start-page: 10203
  year: 2012
  ident: WOS:000311872200019
  article-title: Influence of Connector Groups on the Interactions of Substituents with Carbon-Centered Radicals
  publication-title: JOURNAL OF PHYSICAL CHEMISTRY A
  doi: 10.1021/jp3064245
– volume: 451
  start-page: 417
  year: 2008
  ident: WOS:000252554100035
  article-title: Catalytic C-H functionalization by metal carbenoid and nitrenoid insertion
  publication-title: NATURE
  doi: 10.1038/nature06485
– volume: 41
  start-page: 215
  year: 2012
  ident: WOS:000303273800004
  article-title: Synthesis of Dibenz[a,h]anthracenes by Pd-Catalyzed Intramolecular Double-cyclization of (Z,Z)-p-Styrylstilbenes
  publication-title: CHEMISTRY LETTERS
  doi: 10.1246/cl.2012.215
– year: 2009
  ident: 000415785900035.55
  publication-title: CYLview, 1.0b
– volume: 15
  start-page: 920
  year: 2017
  ident: WOS:000394955200021
  article-title: Effect of solvent on radical cyclisation pathways: SRN1 vs. aryl-aryl bond forming mechanisms
  publication-title: ORGANIC & BIOMOLECULAR CHEMISTRY
  doi: 10.1039/c6ob02684b
– volume: 135
  start-page: 5565
  year: 2013
  ident: WOS:000317872800020
  article-title: Carbamoyl Anion Addition to N-Sulfinyl Imines: Highly Diastereoselective Synthesis of α-Amino Amides
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/ja402647m
– volume: 5
  start-page: 474
  year: 2013
  ident: WOS:000319404900009
  article-title: Switching radical stability by pH-induced orbital conversion
  publication-title: NATURE CHEMISTRY
  doi: 10.1038/NCHEM.1625
– volume: 16
  start-page: 558
  year: 1883
  ident: 000415785900035.48
  publication-title: Ber. Dtsch. Chem. Ges
– volume: 52
  start-page: 7138
  year: 2016
  ident: WOS:000377083300017
  article-title: Double C-H amination by consecutive SET oxidations
  publication-title: CHEMICAL COMMUNICATIONS
  doi: 10.1039/c6cc03106d
– volume: 52
  start-page: 2194
  year: 2013
  ident: WOS:000314998500009
  article-title: Intramolecular C(sp3)-N Coupling by Oxidation of Benzylic C,N-Dianions
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201209591
– volume: 22
  start-page: 14840
  year: 2016
  ident: WOS:000384806700039
  article-title: Facile Synthetic Approach to a Large Variety of Soluble Diarenoperylenes
  publication-title: CHEMISTRY-A EUROPEAN JOURNAL
  doi: 10.1002/chem.201603336
– volume: 23
  start-page: 65
  year: 2017
  ident: WOS:000393599700011
  article-title: N-Methylanilines as Simple and Efficient Promoters for Radical-Type Cross-Coupling Reactions of Aryl Iodides
  publication-title: CHEMISTRY-A EUROPEAN JOURNAL
  doi: 10.1002/chem.201604602
– year: 2017
  ident: 000415785900035.1
  publication-title: IQmol, 2. 8. 0
– volume: 349
  start-page: 1326
  year: 2015
  ident: WOS:000361357700046
  article-title: Site-selective arene C-H amination via photoredox catalysis
  publication-title: SCIENCE
  doi: 10.1126/science.aac9895
– volume: 82
  start-page: 5731
  year: 2017
  ident: WOS:000402851000022
  article-title: Impact of Conjugation and Hyperconjugation on the Radical Stability of Allylic and Benzylic Systems: A Theoretical Study
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/acs.joc.7b00549
– volume: 54
  start-page: 10587
  year: 2015
  ident: WOS:000360312800034
  article-title: Transition-Metal-Free -Arylation of Enolizable Aryl Ketones and Mechanistic Evidence for a Radical Process
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201502332
– volume: 139
  start-page: 18512
  year: 2017
  ident: WOS:000419082100023
  article-title: Synthesis, Structures, and Properties of Hexapole Helicenes: Assembling Six [5]Helicene Substructures into Highly Twisted Aromatic Systems
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.7b07113
– volume: 120
  start-page: 264
  year: 1998
  ident: WOS:000071624500004
  article-title: Structure and morphology of helicene fibers
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
– volume: 2
  start-page: 753
  year: 2017
  ident: WOS:000408621400003
  article-title: Photoredox-Initiated Radical Cascades Enabling Collective Synthesis of 33 Natural Products
  publication-title: CHEM
  doi: 10.1016/j.chempr.2017.05.018
– volume: 116
  start-page: 12381
  year: 2012
  ident: WOS:000312519800021
  article-title: Heteroatomic Deprotonation of Substituted Methanes and Methyl Radicals: Theoretical Insights into Structure, Stability, and Thermochemistry
  publication-title: JOURNAL OF PHYSICAL CHEMISTRY A
  doi: 10.1021/jp3101927
– volume: 131
  start-page: 11707
  year: 2009
  ident: WOS:000269379400030
  article-title: Allylic C-H Amination for the Preparation of syn-1,3-Amino Alcohol Motifs
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/ja9054959
– volume: 75
  start-page: 8689
  year: 2010
  ident: WOS:000285081100046
  article-title: Fast Oxy-Cope Rearrangements of Bis-alkynes: Competition with Central C-C Bond Fragmentation and Incorporation in Tunable Cascades Diverging from a Common Bis-allenic Intermediate
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/jo101838a
– volume: 138
  start-page: 15617
  year: 2016
  ident: WOS:000389623800021
  article-title: Orbital Crossings Activated through Electron Injection: Opening Communication between Orthogonal Orbitals in Anionic C1-C5 Cyclizations of Enediynes
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.6b08540
– volume: 6
  start-page: 4791
  year: 2004
  ident: WOS:000225548600038
  article-title: Oxygenation of benzyldimethylamine by singlet oxygen. Products and mechanism
  publication-title: ORGANIC LETTERS
  doi: 10.1021/ol047876l
– volume: 42
  start-page: 3427
  year: 1909
  ident: WOS:000201158100075
  article-title: About a new formation of N-alkalized Pyrrolidine.
  publication-title: BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT
– volume: 79
  start-page: 3731
  year: 2014
  ident: WOS:000335490700001
  article-title: Discovery and Development of Organic Super-Electron-Donors
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/jo500071u
– volume: 138
  start-page: 7402
  year: 2016
  ident: WOS:000378193300032
  article-title: KOtBu: A Privileged Reagent for Electron Transfer Reactions?
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.6b03282
– volume: 15
  start-page: 6780
  year: 2009
  ident: WOS:000268286200001
  article-title: N-Heteroacenes
  publication-title: CHEMISTRY-A EUROPEAN JOURNAL
  doi: 10.1002/chem.200900990
– volume: 58
  start-page: 6410
  year: 1993
  ident: WOS:A1993MF51600041
  article-title: BOND-DISSOCIATION ENERGIES OF THE N-H BONDS IN ANILINES AND IN THE CORRESPONDING RADICAL-ANIONS - EQUILIBRIUM ACIDITIES OF ANILINE RADICAL CATIONS
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
– volume: 76
  start-page: 577
  year: 2004
  ident: WOS:000221367800013
  article-title: Application of C-H and C-C bond activation in organic synthesis
  publication-title: PURE AND APPLIED CHEMISTRY
– volume: 45
  start-page: 3129
  year: 1967
  ident: WOS:A1967A405700016
  article-title: SOME ACID-BASE REACTIONS IN STRONGLY ALKALINE ANHYDROUS SOLVANTS .I. ETHYLENEDIAMINE
  publication-title: CANADIAN JOURNAL OF CHEMISTRY
– volume: 6
  start-page: 661
  year: 2014
  ident: WOS:000341371100004
  article-title: C-H ACTIVATION The road less travelled to amination
  publication-title: NATURE CHEMISTRY
  doi: 10.1038/nchem.2018
– volume: 138
  start-page: 1792
  year: 2016
  ident: WOS:000370582900013
  article-title: Coronene-Containing N-Heteroarenes: 13 Rings in a Row
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.5b12642
– volume: 15
  start-page: 53
  year: 2009
  ident: WOS:000262301900008
  article-title: Fast Access to Robust C-Sialoside Multimers
  publication-title: CHEMISTRY-A EUROPEAN JOURNAL
  doi: 10.1002/chem.200801810
– volume: 43
  start-page: 399
  year: 2002
  ident: WOS:000173262000014
  article-title: An efficient method for the N-debenzylation of aromatic heterocycles
  publication-title: TETRAHEDRON LETTERS
– volume: 77
  start-page: 4774
  year: 2012
  ident: WOS:000304129400029
  article-title: Conversion and Origin of Normal and Abnormal Temperature Dependences of Kinetic Isotope Effect in Hydride Transfer Reactions
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/jo3005952
– volume: 132
  year: 2010
  ident: WOS:000415785900035.40
  publication-title: J CHEM PHYS
– volume: 30
  start-page: ARTN e3744
  year: 2017
  ident: WOS:000409339500016
  article-title: Electrochemical behavior of N-oxyphthalimides: Cascades initiating self-sustaining catalytic reductive N-O bond cleavage
  publication-title: JOURNAL OF PHYSICAL ORGANIC CHEMISTRY
  doi: 10.1002/poc.3744
– volume: 46
  start-page: 392
  year: 2017
  ident: WOS:000396062600018
  article-title: Bronsted Acid-catalyzed Tandem Cycloaromatization of Naphthalene-based Bisacetals: Selective Synthesis of ortho-Fused Six-hexagon Benzenoids
  publication-title: CHEMISTRY LETTERS
  doi: 10.1246/cl.161122
– volume: 105
  start-page: 3842
  year: 2005
  ident: WOS:000232755200014
  article-title: Nucleus-independent chemical shifts (NICS) as an aromaticity criterion
  publication-title: CHEMICAL REVIEWS
  doi: 10.1021/cr030088+
– volume: 52
  start-page: 2239
  year: 2013
  ident: WOS:000314998500019
  article-title: Metal-Free Reductive Cleavage of Benzylic Esters and Ethers: Fragmentations Result from Single and Double Electron Transfers
  publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  doi: 10.1002/anie.201208066
– year: 1000
  ident: 000415785900035.77
  publication-title: Aroma
– volume: 137
  start-page: 9226
  year: 2015
  ident: WOS:000358896600008
  article-title: Catalytic Alkene Carboaminations Enabled by Oxidative Proton-Coupled Electron Transfer
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.5b05377
– start-page: 3113
  year: 1951
  ident: WOS:A1951UB66700067
  article-title: SYNTHESES OF POLYCYCLIC SYSTEMS .1. A NEW SYNTHESIS OF PHENANTHRIDINE AND PHENANTHRIDINE DERIVATIVES
  publication-title: JOURNAL OF THE CHEMICAL SOCIETY
– volume: 139
  start-page: 6867
  year: 2017
  ident: WOS:000402498500022
  article-title: Potassium tert-Butoxide-Catalyzed Dehydrogenative C-H Silylation of Heteroaromatics: A Combined Experimental and Computational Mechanistic Study
  publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  doi: 10.1021/jacs.6b13031
– volume: 5
  start-page: ARTN 4707
  year: 2014
  ident: WOS:000341078900005
  article-title: Silver-catalysed direct amination of unactivated C-H bonds of functionalized molecules
  publication-title: NATURE COMMUNICATIONS
  doi: 10.1038/ncomms5707
– volume: 111
  start-page: 9978
  year: 2007
  ident: WOS:000249838100042
  article-title: Computation of pKa values of substituted aniline radical cations in dimethylsulfoxide solution
  publication-title: JOURNAL OF PHYSICAL CHEMISTRY A
  doi: 10.1021/jp072456+
– volume: 75
  start-page: 2281
  year: 2010
  ident: WOS:000275884400015
  article-title: Obtaining Relative Induced Ring Currents Quantitatively from NICS
  publication-title: JOURNAL OF ORGANIC CHEMISTRY
  doi: 10.1021/jo1000753
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Snippet An intramolecular oxidative C­(sp3)–H amination from unprotected anilines and C­(sp3)–H bonds readily occurs under mild conditions using t-BuOK, molecular...
An intramolecular oxidative C(sp(3))-H amination from unprotected anilines and C(sp(3))-H bonds readily occurs under mild conditions using t-BuOK, molecular...
An intramolecular oxidative C(sp )-H amination from unprotected anilines and C(sp )-H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen...
An intramolecular oxidative C(sp3)-H amination from unprotected anilines and C(sp3)-H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen...
An intramolecular oxidative C(sp³)–H amination from unprotected anilines and C(sp³)–H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen...
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SubjectTerms acidity
amination
aromatic compounds
carbon-hydrogen bond activation
chemical bonding
Chemistry
Chemistry, Multidisciplinary
dimethylformamide
heterocyclic nitrogen compounds
oxidants
oxidation
oxygen
Physical Sciences
Science & Technology
transition elements
Title Coupling N–H Deprotonation, C–H Activation, and Oxidation: Metal-Free C(sp3)–H Aminations with Unprotected Anilines
URI http://dx.doi.org/10.1021/jacs.7b07519
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestApp=WOS&DestLinkType=FullRecord&UT=000415785900035
https://www.ncbi.nlm.nih.gov/pubmed/29037029
https://www.proquest.com/docview/1952107232
https://www.proquest.com/docview/2116893134
Volume 139
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