Drug Delivery Using Stimuli-Responsive Polymer Gel Spheres

• Published in: Industrial & engineering chemistry research Vol. 51; no. 4; pp. 1741 - 1755
• Main Authors: Ninawe, Pravin R, Parulekar, Satish J
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 01.02.2012
• Subjects: Applied sciences; Chemical engineering; deformation; diffusivity; Displacement; drug carriers; Drug delivery systems; Drugs; engineering; Exact sciences and technology; gels; Macromolecules; Materials and Interfaces; Mathematical models; Networks; polymers; porosity; solvents; Swelling; temperature; Uptakes

Polymeric gels that undergo deformation upon appropriate changes in pH or temperature have considerable promise as drug delivery vehicles. Uptake of drug macromolecules into swelling and nonswelling gel spheres and release of drug macromolecules from deswelling and nondeforming gel spheres into a ta...