Combined Gelatin−Chondroitin Sulfate Hydrogels for Controlled Release of Cationic Antibacterial Proteins

• Published in: Macromolecules Vol. 33; no. 10; pp. 3705 - 3713
• Main Authors: Kuijpers, Alma J, Engbers, Gerard H. M, Meyvis, Tom K. L, de Smedt, Stefaan S. C, Demeester, Joseph, Krijgsveld, Jeroen, Zaat, Sebastian A. J, Dankert, Jacob, Feijen, Jan
• Format: Journal Article
• Language: English
• Published: American Chemical Society 16.05.2000
• Subjects: Adsorbents; Biomaterials; Crosslinking; Diffusion in solids; Gels; Proteins; Rheology; Sulfur compounds; Swelling

Chemically cross-linked gelatin−chondroitin sulfate (ChS) hydrogels were prepared for the controlled release of small cationic proteins. The amount of chondroitin sulfate in the gelatin gels varied between 0 and 20 wt %. The chemical cross-link density, the degree of swelling, and the rheological be...