Transition Metal-Catalyzed Tandem Reactions of Ynamides for Divergent N‑Heterocycle Synthesis

• Published in: Accounts of chemical research Vol. 53; no. 9; pp. 2003 - 2019
• Main Authors: Hong, Feng-Lin, Ye, Long-Wu
• Format: Journal Article
• Language: English
• Published: American Chemical Society 15.09.2020

Conspectus Ynamides are electron-rich heteroatom-substituted alkynes with a C–C triple bond directly attached to the amide group. Importantly, this amide group is able to impose an electronic bias, thus resulting in the highly regioselective attack of this polarized alkyne by a large variety of nucl...