Dehydrogenation/(3+2) Cycloaddition of Saturated Aza-Heterocycles via Merging Organic Photoredox and Lewis Acid Catalysis

• Published in: Organic letters Vol. 23; no. 22; pp. 8942 - 8946
• Main Authors: Xiao, Teng-Fei, Zhang, Yi-Fan, Hou, Wen-Tao, Yan, Pen-Ji, Hai, Jun, Xu, Peng-Fei, Xu, Guo-Qiang
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 19.11.2021; Amer Chemical Soc
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; FUNCTIONALIZATION; LIGHT ALKANES; AMINES; C-H ACTIVATION; CYCLIZATION; METATHESIS

Herein, we report a photoinduced dehydrogenation/(3+2) cycloaddition reaction by merging organic photoredox and Lewis acid catalysis, providing a straightforward and efficient approach for directly installing a benzofuran skeleton on the saturated aza-heterocycles. In this protocol, we also describe...