Impact of Dehydroamino Acids on the Structure and Stability of Incipient 310-Helical Peptides
A comparative study of the impact of small, medium-sized, and bulky α,β-dehydroamino acids (ΔAAs) on the structure and stability of Balaram’s incipient 310-helical peptide (1) is reported. Replacement of the N-terminal Aib residue of 1 with a ΔAA afforded peptides 2a–c that maintained the 310-helica...
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Published in | Journal of organic chemistry Vol. 85; no. 3; pp. 1601 - 1613 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
WASHINGTON
American Chemical Society
07.02.2020
Amer Chemical Soc |
Subjects | |
Online Access | Get full text |
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