A Highly Sensitive Plasmonic DNA Assay Based on Triangular Silver Nanoprism Etching

• Published in: ACS nano Vol. 8; no. 5; pp. 4902 - 4907
• Main Authors: Yang, Xinjian, Yu, Yuebo, Gao, Zhiqiang
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 27.05.2014
• Subjects: Biosensing Techniques; DNA - chemistry; Electrophoresis, Polyacrylamide Gel; Enzymes - chemistry; Glucose - chemistry; Humans; Metal Nanoparticles - chemistry; Microarray Analysis - instrumentation; Microarray Analysis - methods; Microscopy, Electron, Transmission; Nanotechnology - methods; Nucleic Acid Hybridization; Nucleic Acids - chemistry; Sensitivity and Specificity; Silver - chemistry; Silver Compounds - chemistry; Spectrophotometry, Ultraviolet; Surface Plasmon Resonance; plasmonic biosensor; silver nanoprism; etching; signal amplification; DNA assay; HCR

Specific nucleic acid detection by using simple and low-cost assays is important in clinical diagnostics, mutation detection, and biodefense applications. Most current methods for the quantification of low concentrations of DNA require costly and sophisticated instruments. Here, we have developed a...