Photodynamic and Photothermal Effects of Semiconducting and Metallic-Enriched Single-Walled Carbon Nanotubes

• Published in: Journal of the American Chemical Society Vol. 134; no. 43; pp. 17862 - 17865
• Main Authors: Murakami, Tatsuya, Nakatsuji, Hirotaka, Inada, Mami, Matoba, Yoshinori, Umeyama, Tomokazu, Tsujimoto, Masahiko, Isoda, Seiji, Hashida, Mitsuru, Imahori, Hiroshi
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 31.10.2012
• Subjects: Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Cell Line, Tumor; Cell Survival - drug effects; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Nanotubes, Carbon - chemistry; Photosensitizing Agents - chemistry; Photosensitizing Agents - pharmacology; Reactive Oxygen Species - metabolism; Semiconductors; Structure-Activity Relationship; Temperature

Semiconducting and metallic single-walled carbon nanotubes (s-SWNTs and m-SWNTs) were enriched by agarose gel chromatography and their photothermal and photodynamic effects were compared in H2O. Under near-infrared laser irradiation, s-SWNTs generated reactive oxygen species (ROS) more than m-SWNTs,...