Quantification of Cholesterol Solubilized in Dietary Micelles: Dependence on Human Bile Salt Variability and the Presence of Dietary Food Ingredients

• Published in: Langmuir Vol. 32; no. 18; pp. 4564 - 4574
• Main Authors: Coreta-Gomes, Filipe M, Vaz, Winchil L. C, Wasielewski, Emeric, Geraldes, Carlos F. G, Moreno, Maria João
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 10.05.2016
• Subjects: absorption; atherosclerosis; bile salts; blood; cholesterol; coprecipitation; diet; humans; ingredients; Interface Components: Nanops, Colloids, Emulsions, Surfactants, Proteins, Polymers; intestinal mucosa; micelles; oleic acid; palmitic acid; solubility; solubilization; stigmasterol

The solubility of cholesterol in bile salt (BS) micelles is important to understand the availability of cholesterol for absorption in the intestinal epithelium and to develop strategies to decrease cholesterol intake from the intestinal lumen. This has been the subject of intense investigation, due...