Peroxides as “Switches” of Dialkyl H‑Phosphonate: Two Mild and Metal-Free Methods for Preparation of 2‑Acylbenzothiazoles and Dialkyl Benzothiazol-2-ylphosphonates

• Published in: Journal of organic chemistry Vol. 79; no. 17; pp. 8407 - 8416
• Main Authors: Chen, Xiao-Lan, Li, Xu, Qu, Ling-Bo, Tang, Yu-Chun, Mai, Wen-Peng, Wei, Dong-Hui, Bi, Wen-Zhu, Duan, Li-Kun, Sun, Kai, Chen, Jian-Yu, Ke, Dian-Dian, Zhao, Yu-Fen
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 05.09.2014; Amer Chemical Soc
• Subjects: Benzothiazoles - chemical synthesis; Benzothiazoles - chemistry; Catalysis; Chemistry; Chemistry, Organic; Metals; Molecular Structure; Organophosphonates - chemistry; Peroxides - chemistry; Physical Sciences; Science & Technology; DESIGN; ACID; BIOLOGICAL EVALUATION; ARYL; INHIBITORS; TRANSFORMYLASE; ALKYNES; DERIVATIVES; BENZOTHIAZOLES

Two mild and metal-free methods for the preparation of two kinds of important benzothiazole derivatives, 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates, respectively, were developed. The dialkyl H-phosphonate (RO)2P(O)H exists in equilibrium with its tautomer dialkyl phosphite (RO)2P...