Cladribine and Fludarabine Nucleoside Change the Levels of CD Antigens on B-Lymphoproliferative Disorders

• Published in: International Journal of Proteomics Vol. 2010; no. 2010; pp. 86 - 94
• Main Authors: Mactier, Swetlana, Cassano, Carlos, Mulligan, Stephen P., Belov, Larissa, Huang, Pauline, Christopherson, Richard I.
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Limiteds 01.01.2010; Hindawi Puplishing Corporation; Hindawi Publishing Corporation

The purine analogs, fludarabine nucleoside (FdA), and cladribine (CdA) (1 μM, 24 hours), significantly changed the levels of some surface antigens on the human B-cell lines MEC2 and Raji. Changes in the surface proteins were identified using a Cluster of Differentiation (CD) antibody microarray that...