Photophysical Studies on the Supramolecular Photochirogenesis for the Photocyclodimerization of 2-Anthracenecarboxylate within Human Serum Albumin

• Published in: The journal of physical chemistry. B Vol. 113; no. 30; pp. 10445 - 10453
• Main Authors: Pace, Tamara C. S, Nishijima, Masaki, Wada, Takehiko, Inoue, Yoshihisa, Bohne, Cornelia
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 30.07.2009
• Subjects: Anthracenes - chemistry; Anthracenes - metabolism; B: Biophysical Chemistry; Binding Sites; Binding, Competitive; Carboxylic Acids - chemistry; Carboxylic Acids - metabolism; Humans; Iodobenzoates - metabolism; Iodobenzoates - pharmacology; Methane - analogs & derivatives; Methane - metabolism; Methane - pharmacology; Nitroparaffins - metabolism; Nitroparaffins - pharmacology; Photolysis; Serum Albumin - antagonists & inhibitors; Serum Albumin - metabolism; Spectrometry, Fluorescence; Stereoisomerism; Substrate Specificity; Time Factors

The mechanism for the chirogenesis in the photocyclodimerization of 2-anthracenecarboxylate (AC) bound to human serum albumin (HSA) was investigated using time-resolved fluorescence measurements in the presence of HSA inhibitors and/or an AC singlet excited state quencher. The photophysical studies...