Catalytic Acid−Base Groups in Yeast Pyruvate Decarboxylase. 3. A Steady-State Kinetic Model Consistent with the Behavior of both Wild-Type and Variant Enzymes at All Relevant pH Values - Sergienko, Eduard A; Jordan, Frank (Biochemistry (Easton), 2001)
Keywords: Acetaldehyde - metabolism; Alanine - genetics; Amino Acid Substitution - genetics; Asparagine - genetics; Aspartic Acid - genetics; Binding Sites - genetics; Catalytic Domain - genetics; Computer Simulation; Glutamic Acid - genetics; Glutamine - genetics; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Pyruvate Decarboxylase - antagonists & inhibitors; Pyruvate Decarboxylase - chemistry; Pyruvate Decarboxylase - genetics; Pyruvates - chemistry; Recombinant Proteins - antagonists & inhibitors; Recombinant Proteins - chemistry; Saccharomyces cerevisiae - enzymology; Saccharomyces cerevisiae - genetics; Substrate Specificity - genetics