d -Cycloserine Augmentation for Behavioral Therapy

• Published in: The American journal of psychiatry Vol. 165; no. 8; p. 1050
• Main Authors: SHIM, SEONG S., HAMMONDS, MICHAEL D., VRABEL, MATTHEW M.
• Format: Journal Article
• Language: English
• Published: United States American Psychiatric Association 01.08.2008
• Subjects: Alzheimer's disease; Antimetabolites - pharmacology; Antimetabolites - therapeutic use; Cognitive Therapy - methods; Combined Modality Therapy; Cycloserine - pharmacology; Cycloserine - therapeutic use; Glycine - antagonists & inhibitors; Health psychology; Humans; Neuroses; Obsessive-Compulsive Disorder - drug therapy; Obsessive-Compulsive Disorder - therapy; Schizophrenia; Therapy

Since the NMDA receptor is crucial in the domains of learning and memory, the Wilhelm et al. study sought to enhance the learning that occurs during behavioral therapy sessions by potentiating the NMDA receptor via stimulation of the glycine site using D-cycloserine. D-Cycloserine is effective in st...