Ruthenium-Catalyzed C–H Bond Arylations of Arenes Bearing Removable Directing Groups via Six-Membered Ruthenacycles

• Published in: Organic letters Vol. 14; no. 4; pp. 1154 - 1157
• Main Authors: Ackermann, Lutz, Diers, Emelyne, Manvar, Atul
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 17.02.2012; Amer Chemical Soc
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; FUNCTIONALIZATION; SYSTEM; PRELIGANDS; PALLADIUM; ACTIVATION; PHENOLS; ARYL; PHOSPHINE OXIDES; BROMIDES

Ruthenium-catalyzed direct arylations of phenols bearing removable directing groups were accomplished through carboxylate assistance via six-membered ruthenacycles as key intermediates.