Enhanced Analysis of the Mouse Plasma Proteome Using Cysteine-Containing Tryptic Glycopeptides

• Published in: Journal of proteome research Vol. 6; no. 3; pp. 987 - 995
• Main Authors: Bernhard, Oliver K, Kapp, Eugene A, Simpson, Richard J
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 01.03.2007
• Subjects: Animals; Blood Proteins - analysis; Chromatography, Liquid; Cysteine; Glycopeptides; Glycosylation; Mice; Mice, Inbred C57BL; Proteomics - methods; Tandem Mass Spectrometry; Trypsin

A comprehensive understanding of the mouse plasma proteome is important for studies using mouse models to identify protein markers of human disease. To enhance our analysis of the mouse plasma proteome, we have developed a method for isolating low-abundance proteins using a cysteine-containing glyco...