Hydrogen Bonds: Simple after All?

• Published in: Biochemistry (Easton) Vol. 57; no. 24; pp. 3338 - 3352
• Main Authors: Herschlag, Daniel, Pinney, Margaux M
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 19.06.2018
• Subjects: catalytic activity; Hydrogen Bonding; Molecular Structure; prediction; proteins; Salicylates - chemistry; Thermodynamics

Hydrogen bonds play integral roles in biological structure, function, and conformational dynamics and are fundamental to life as it has evolved on Earth. However, our understanding of these fundamental and ubiquitous interactions has seemed fractured and incomplete, and it has been difficult to extr...