Design, Synthesis, and Insecticidal Evaluation of New Benzoylureas Containing Isoxazoline and Isoxazole Group

Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by 1H NMR and elemental analysis (or HRMS). The larvicidal activities against Oriental armyworm, mosquito, and diamondback moth of the new compounds...

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Published inJournal of agricultural and food chemistry Vol. 59; no. 9; pp. 4851 - 4859
Main Authors Sun, Ranfeng, Li, Yongqiang, Xiong, Lixia, Liu, Yuxiu, Wang, Qingmin
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 11.05.2011
Amer Chemical Soc
Subjects
Agriculture
Agriculture, Multidisciplinary
Animals
benzoylphenylureas
Biological and medical sciences
chemical synthesis
Chemistry
Chemistry, Applied
Crop and Animal Protection Chemistry
Culicidae
Culicidae - drug effects
Drug Design
drug effects
Food industries
Food Science & Technology
Fundamental and applied biological sciences. Psychology
insecticidal properties
insecticides
Insecticides - chemical synthesis
Insecticides - chemistry
Insecticides - pharmacology
Isoxazoles
Isoxazoles - chemical synthesis
Isoxazoles - chemistry
Isoxazoles - pharmacology
Life Sciences & Biomedicine
Moths
Moths - drug effects
nuclear magnetic resonance spectroscopy
pharmacology
Physical Sciences
Plutella xylostella
Science & Technology
Structure-Activity Relationship
Urea
Urea - chemical synthesis
Urea - chemistry
Urea - pharmacology
isoxazoline
Benzoylphenylureas
insecticidal activity
isoxazole
insect growth regulator
benzoyl urea
BIOACTIVITY
OXIME ETHER
QSAR
SAR
CHITIN SYNTHESIS
Evaluation
Insecticide
Growth
Insecta
Pesticides
Design
Urea
Synthesis
Arthropoda
Ureas
Invertebrata
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Abstract Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by 1H NMR and elemental analysis (or HRMS). The larvicidal activities against Oriental armyworm, mosquito, and diamondback moth of the new compounds were evaluated. Compounds I-1 and III-1 showed nearly the same level of insecticidal activity against Oriental armyworm as commercial insecticide Flucycloxuron and surprisingly exhibited much higher larvicidal activities against diamondback moth than Flucycloxuron.
AbstractList Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by (1)H NMR and elemental analysis (or HRMS). The larvicidal activities against Oriental armyworm, mosquito, and diamondback moth of the new compounds were evaluated. Compounds I-1 and III-1 showed nearly the same level of insecticidal activity against Oriental armyworm as commercial insecticide Flucycloxuron and surprisingly exhibited much higher larvicidal activities against diamondback moth than Flucycloxuron.
Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by 1H NMR and elemental analysis (or HRMS). The larvicidal activities against Oriental armyworm, mosquito, and diamondback moth of the new compounds were evaluated. Compounds I-1 and III-1 showed nearly the same level of insecticidal activity against Oriental armyworm as commercial insecticide Flucycloxuron and surprisingly exhibited much higher larvicidal activities against diamondback moth than Flucycloxuron.
Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by H-1 NMR and elemental analysis (or FIRMS). The larvicidal activities against Oriental armyworm, mosquito, and diamondback moth of the new compounds were evaluated. Compounds I-1 and III-1 showed nearly the same level of insecticidal activity against Oriental armyworm as commercial insecticide Flucycloxuron and surprisingly exhibited much higher larvicidal activities against diamondback moth than Flucycloxuron.
Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by (1)H NMR and elemental analysis (or HRMS). The larvicidal activities against Oriental armyworm, mosquito, and diamondback moth of the new compounds were evaluated. Compounds I-1 and III-1 showed nearly the same level of insecticidal activity against Oriental armyworm as commercial insecticide Flucycloxuron and surprisingly exhibited much higher larvicidal activities against diamondback moth than Flucycloxuron.Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by (1)H NMR and elemental analysis (or HRMS). The larvicidal activities against Oriental armyworm, mosquito, and diamondback moth of the new compounds were evaluated. Compounds I-1 and III-1 showed nearly the same level of insecticidal activity against Oriental armyworm as commercial insecticide Flucycloxuron and surprisingly exhibited much higher larvicidal activities against diamondback moth than Flucycloxuron.
Author Li, Yongqiang
Xiong, Lixia
Sun, Ranfeng
Liu, Yuxiu
Wang, Qingmin
AuthorAffiliation Nankai University
AuthorAffiliation_xml – name: Nankai University
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  surname: Sun
  fullname: Sun, Ranfeng
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  givenname: Yongqiang
  surname: Li
  fullname: Li, Yongqiang
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  givenname: Lixia
  surname: Xiong
  fullname: Xiong, Lixia
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  givenname: Qingmin
  surname: Wang
  fullname: Wang, Qingmin
  email: wang98h@263.net, wangqm@nankai.edu.cn
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Issue 9
Keywords isoxazoline
Benzoylphenylureas
insecticidal activity
isoxazole
insect growth regulator
benzoyl urea
BIOACTIVITY
OXIME ETHER
QSAR
SAR
CHITIN SYNTHESIS
Evaluation
Insecticide
Growth
Insecta
Pesticides
Design
Urea
Synthesis
Arthropoda
Ureas
Invertebrata
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Snippet Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by 1H...
Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by H-1...
Twenty-two new benzoylphenylureas containing isoxazoline and the isoxazole group were designed and synthesized, and their structures were characterized by (1)H...
Source Web of Science
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SubjectTerms Agriculture
Agriculture, Multidisciplinary
Animals
benzoylphenylureas
Biological and medical sciences
chemical synthesis
Chemistry
Chemistry, Applied
Crop and Animal Protection Chemistry
Culicidae
Culicidae - drug effects
Drug Design
drug effects
Food industries
Food Science & Technology
Fundamental and applied biological sciences. Psychology
insecticidal properties
insecticides
Insecticides - chemical synthesis
Insecticides - chemistry
Insecticides - pharmacology
Isoxazoles
Isoxazoles - chemical synthesis
Isoxazoles - chemistry
Isoxazoles - pharmacology
Life Sciences & Biomedicine
Moths
Moths - drug effects
nuclear magnetic resonance spectroscopy
pharmacology
Physical Sciences
Plutella xylostella
Science & Technology
Structure-Activity Relationship
Urea
Urea - chemical synthesis
Urea - chemistry
Urea - pharmacology
Title Design, Synthesis, and Insecticidal Evaluation of New Benzoylureas Containing Isoxazoline and Isoxazole Group
URI http://dx.doi.org/10.1021/jf200395g
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestApp=WOS&DestLinkType=FullRecord&UT=000290120400065
https://www.ncbi.nlm.nih.gov/pubmed/21438557
https://www.proquest.com/docview/1999989672
https://www.proquest.com/docview/864964892
Volume 59
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