Extended Spectrum β-Lactamase Activity and Cephalosporin Resistance in Escherichia coli from U.S. Mid-Atlantic Surface and Reclaimed Water

• Published in: Applied and environmental microbiology Vol. 88; no. 15; p. e0083722
• Main Authors: Solaiman, Sultana, Handy, Eric, Brinks, Taylor, Goon, Kasey, Bollinger, Chris, Sapkota, Amy R, Sharma, Manan, Micallef, Shirley A
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 09.08.2022
• Subjects: Amides; Anti-Bacterial Agents - pharmacology; Antibiotics; Antimicrobial resistance; beta-Lactamases - genetics; Cefotaxime; Cefoxitin; Ceftazidime; Ceftriaxone; Cefuroxime; Cephalosporin Resistance - genetics; Cephalosporins; Cephalosporins - pharmacology; Drug resistance; E coli; Environmental Microbiology; Escherichia coli; Escherichia coli Infections - microbiology; Homogeneity; Humans; Irrigation water; M gene; Phylogeny; Ponds; Public and Environmental Health Microbiology; Reclaimed water; Reclamation; Resistance factors; Rivers; Surface water; Water isolates; β Lactamase; β-Lactam antibiotics; United States > US; ESBL-producing Escherichia coli; reclaimed wastewater for irrigation; antimicrobial resistance genes; β-lactam resistance; cephalosporin resistance; irrigation water

Phylogenetic distribution and extended spectrum β-lactamase (ESBL) activity of Escherichia coli recovered from surface and reclaimed water in the mid-Atlantic U.S. were evaluated. Among 488 isolates, phylogroups B1 and A were the most and least prevalent, respectively. Water type, but not season, af...