Multiscale Modeling of Respiratory Transport Phenomena and Intersubject Variability

• Published in: Annual review of fluid mechanics Vol. 57; no. 1; pp. 141 - 165
• Main Authors: Kassinos, Stavros C, Sznitman, Josué
• Format: Journal Article
• Language: English
• Published: Annual Reviews 22.01.2025
• Subjects: chronic pulmonary disease; in silico population studies; intersubject variability; pulmonary drug delivery; respiratory flows; whole-lung models

Our understanding of respiratory flow phenomena has been consolidated over decades with the exploration of in vitro and in silico canonical models that underscore the multiscale fluid mechanics spanning the vast airway complex. In recent years, there has been growing recognition of the significant i...