Scalable Process Design for a PDE10A Inhibitor Consisting of Pyrazolopyrimidine and Quinoxaline as Key Units - Yamagami, Takafumi; Kobayashi, Ryo; Moriyama, Noriaki; Horiuchi, Hideki; Toyofuku, Eiji; Kadoh, Yoichi; Kawanishi, Eiji; Izumoto, Shinichi; Hiramatsu, Hajime; Nanjo, Takehiro; Sugino, Masuhiro; Utsugi, Masayuki; et al. (Organic Process Research & Development, 2019)
Keywords: Chemistry; Chemistry, Applied; Chemistry, Organic; Physical Sciences; Science & Technology; scale-up; pyrazolo[1,5-a]pyrimidines; PDE10A inhibitors; quinoxalines; nucleophilic aromatic substitution reactions