The Clinical Effectiveness and Cost-effectiveness of Screening for Anal Squamous Intraepithelial Lesions in Homosexual and Bisexual HIV-Positive Men

• Published in: JAMA : the journal of the American Medical Association Vol. 281; no. 19; pp. 1822 - 1829
• Main Authors: Goldie, Sue J, Kuntz, Karen M, Weinstein, Milton C, Freedberg, Kenneth A, Welton, Mark L, Palefsky, Joel M
• Format: Journal Article
• Language: English
• Published: Chicago, IL American Medical Association 19.05.1999
• Subjects: Adult; AIDS/HIV; Anus Neoplasms - complications; Anus Neoplasms - diagnosis; Anus Neoplasms - economics; Biological and medical sciences; Bisexuality; Cancer; Carcinoma, Squamous Cell - complications; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - economics; Cost-Benefit Analysis; Cytodiagnosis - economics; Disease Progression; Gastroenterology. Liver. Pancreas. Abdomen; Gays & lesbians; HIV; HIV Infections - complications; HIV Infections - economics; HIV Infections - physiopathology; Homosexuality; Human immunodeficiency virus; Human viral diseases; Humans; Infectious diseases; Male; Markov Chains; Mass Screening - economics; Medical diagnosis; Medical sciences; Medical screening; Precancerous Conditions - complications; Precancerous Conditions - diagnosis; Precancerous Conditions - economics; Quality-Adjusted Life Years; Risk Factors; Sensitivity and Specificity; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Tumors; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; United States; North America; America; Human; Immunopathology; Squamous cell carcinoma; Homosexuality; Sexual behavior; Male; AIDS; Malignant tumor; Bisexuality; Medical screening; Immune deficiency; Epidemiology; Infection; Association; Anus; Efficiency; Viral disease; Health economy; Digestive diseases; Public health; Cost efficiency analysis

CONTEXT Homosexual and bisexual men infected with human immunodeficiency virus (HIV) are at increased risk for human papillomavirus–related anal neoplasia and anal squamous cell carcinoma (SCC). OBJECTIVE To estimate the clinical benefits and cost-effectiveness of screening HIV-positive homosexual a...