Acute Aphasia in Multiple Sclerosis

• Published in: Archives of neurology (Chicago) Vol. 57; no. 8; pp. 1207 - 1209
• Main Authors: Devere, Todd R, Trotter, John L, Cross, Anne H
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Chicago, IL American Medical Association 01.08.2000
• Subjects: Acute Disease; Adult; Anti-Inflammatory Agents - administration & dosage; Aphasia, Broca - diagnosis; Aphasia, Broca - drug therapy; Aphasia, Broca - etiology; Biological and medical sciences; Female; Humans; Magnetic Resonance Imaging; Male; Medical sciences; Methylprednisolone Hemisuccinate - administration & dosage; Middle Aged; Multiple Sclerosis - complications; Multiple Sclerosis - diagnosis; Multiple Sclerosis - drug therapy; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis; Neurology; Case study; Human; Nervous system diseases; Multiple sclerosis; Acute; Central nervous system disease; Aphasia; Complication; Neurological disorder; Language disorder; Cerebral disorder; Inflammatory disease
• DOI: 10.1001/archneur.57.8.1207
• ISSN: 0003-9942; 2168-6149

Acute aphasia is rare in multiple sclerosis. We describe 3 patients with multiple sclerosis who had acute exacerbations presenting as aphasias. One patient had a mixed transcortical aphasia, 1 had a transcortical motor aphasia, and 1 had a Broca aphasia. Magnetic resonance imaging scans of the brain with contrast enhancement revealed new white matter lesions in the left hemisphere in all 3 patients. Two of the 3 patients had a good response to treatment with methylprednisolone sodium succinate.Arch Neurol. 2000;57:1207-1209-->