Characterization and Improvement of Signal Drift Associated with Electron Ionization Quadrupole Mass Spectrometry

• Published in: Analytical chemistry (Washington) Vol. 82; no. 15; pp. 6480 - 6486
• Main Authors: D’Autry, Ward, Wolfs, Kris, Yarramraju, Sitaramaraju, Schepdael, Ann Van, Hoogmartens, Jos, Adams, Erwin
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 01.08.2010
• Subjects: Analytical chemistry; Chemistry; Chromatographic methods and physical methods associated with chromatography; Exact sciences and technology; Gas chromatographic methods; Gases; General, instrumentation; Ion chromatography; Mass spectrometry; Oxygen - chemistry; Simulation; Software; Spectrometric and optical methods; Spectrometry, Mass, Electrospray Ionization - instrumentation; Spectrometry, Mass, Electrospray Ionization - methods; Stainless Steel; Volatilization; Performance evaluation; Electron impact ionization; Support; Ion beam; Instrumentation; Standard; Analyzer; Coatings; Quadrupole spectrometer; Chemical enrichment; Characterization; Degradation; Improvement; Signal; Quantitative analysis; Gold; Factor analysis; Stability; Ion source; Sample; Use; Plate; Gas chromatography; Adsorption; Stainless steel; Instability; Software; Technique; Detection; Mass spectrometry; Electron spectrometry

Quadrupole mass spectrometry with electron ionization (EI-QMS) is a very popular detection technique in combination with gas chromatography. It is deployed for the analysis of volatile and semivolatile analytes in many industry domains. Although a very important factor for quantitative analysis, lit...