Mechanism of Rotenone Toxicity against Plutella xylostella: New Perspective from a Spatial Metabolomics and Lipidomics Study

• Published in: Journal of agricultural and food chemistry Vol. 71; no. 1; pp. 211 - 222
• Main Authors: Li, Ping, Tian, Yongqing, Du, Mingyi, Xie, Qingrong, Chen, Yingying, Ma, Lianlian, Huang, Yudi, Yin, Zhibin, Xu, Hanhong, Wu, Xinzhou
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 11.01.2023
• Subjects: adenosine monophosphate; Agricultural and Environmental Chemistry; Amino Acids - metabolism; Animals; biosynthesis; diacylglycerols; energy; fatty acids; food chemistry; glycerophospholipids; guanosine; inosine; Insecticides - pharmacology; Larva; lipid metabolism; Lipidomics; Moths; pesticides; Pesticides - metabolism; pests; Plutella xylostella; rotenone; Rotenone - toxicity; toxicity; tryptophan; rotenone; Plutella xylostella; mass spectrometry imaging; metabolomics; lipidomics

The botanical pesticide rotenone can effectively control target pest Plutella xylostella, yet insights into in situ metabolic regulation of P. xylostella toward rotenone remain limited. Herein, we demonstrated metabolic expression levels and spatial distribution of rotenone-treated P. xylostella usi...