Synthesis of A‑Type Proanthocyanidins and Their Analogues: A Comprehensive Review

• Published in: Journal of agricultural and food chemistry Vol. 68; no. 31; pp. 8104 - 8118
• Main Authors: Alejo-Armijo, Alfonso, Salido, Sofía, Altarejos, Joaquı́n
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 05.08.2020
• Subjects: chalcone; Chemistry Techniques, Synthetic - methods; developmental stages; flavanols; food chemistry; Lewis acids; Molecular Structure; proanthocyanidins; Proanthocyanidins - chemical synthesis; Proanthocyanidins - chemistry; analogues to A-type PACs; condensed tannins; A-type proanthocyanidins (PACs); 2,8-dioxabicyclo[3.3.1]nonane skeleton; organic synthesis

Proanthocyanidins (PACs) are oligomers or polymers composed of units of flavanols. A-type PACs are a subclass of PACs characterized by the presence of at least a double linkage between two consecutive monomers of flavanol. These A-type PACs are found in some fruits and spices and possess potential h...