Free Fatty Acids Induce Apoptosis of Mammary Epithelial Cells of Ketotic Dairy Cows via the Mito-ROS/NLRP3 Signaling Pathway - Chang, Renxu; Jia, Hongdou; Dong, Zhihao; Xu, Qiushi; Liu, Lei; Majigsuren, Zolzaya; Batbaatar, Tugsjargal; Xu, Chuang; Yang, Qing; Sun, Xudong (Journal of agricultural and food chemistry, 2023)
Keywords: Agricultural and Environmental Chemistry; Animals; apoptosis; Apoptosis - drug effects; Cattle; early lactation; epithelial cells; Epithelial Cells - cytology; Epithelial Cells - drug effects; Epithelial Cells - metabolism; epithelium; Fatty Acids, Nonesterified - pharmacology; Female; food chemistry; inflammasomes; Inflammasomes - metabolism; inflammation; ketosis; Ketosis - drug therapy; Ketosis - metabolism; mammary glands; Mammary Glands, Animal; milk yield; mitochondria; Mitochondria - metabolism; NLR Family, Pyrin Domain-Containing 3 Protein - metabolism; oligomerization; reactive oxygen species; Signal Transduction - drug effects; NLRP3; apoptosis; bovine mammary epithelial cells; Mito-ROS