Painless Evidence-Based Medicine
This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating an introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers. A simplified introductor...
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| Main Authors | , , |
|---|---|
| Format | eBook |
| Language | English |
| Published |
Newark
John Wiley & Sons, Incorporated
2017
Wiley-Blackwell |
| Edition | 2 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating an introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers. A simplified introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers Approaches learning from the vantage point of clinical questions on therapy, diagnosis, prognosis or harm rather than the framework of study designs Provides tables and boxed case studies throughout highlighting key topics, or difficult issues, in an easy to read manner Emphasizes applicability of EBM, encouraging readers to dissect the evidence and how results can be applied to individual patients with different circumstances, varying values and preferences New to the Second Edition are chapters on health screening, clinical practice guidelines, and major updates incorporating recommended trial criteria |
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| AbstractList | This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating an introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers. A simplified introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers Approaches learning from the vantage point of clinical questions on therapy, diagnosis, prognosis or harm rather than the framework of study designs Provides tables and boxed case studies throughout highlighting key topics, or difficult issues, in an easy to read manner Emphasizes applicability of EBM, encouraging readers to dissect the evidence and how results can be applied to individual patients with different circumstances, varying values and preferences New to the Second Edition are chapters on health screening, clinical practice guidelines, and major updates incorporating recommended trial criteria This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating an introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers. A simplified introductory approach to the complex and technical subject of evidence-based medicine from experienced teachers Approaches learning from the vantage point of clinical questions on therapy, diagnosis, prognosis or harm rather than the framework of study designs Provides tables and boxed case studies throughout highlighting key topics, or difficult issues, in an easy to read manner Emphasizes applicability of EBM, encouraging readers to dissect the evidence and how results can be applied to individual patients with different circumstances, varying values and preferences New to the Second Edition are chapters on health screening, clinical practice guidelines, and major updates incorporating recommended trial criteria |
| Author | Dans, Antonio L Silvestre, Maria Asuncion A Dans, Leonila F |
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| DOI | 10.1002/9781119196150 |
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| Discipline | Medicine |
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| Publisher | John Wiley & Sons, Incorporated Wiley-Blackwell |
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| Snippet | This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating... This updated edition of Painless Evidence-Based Medicine presents basic concepts and application of research statistics in simple and practical manner creating... |
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| SubjectTerms | Evidence-based medicine |
| TableOfContents | Question #1: Were the criteria for inclusion of studies appropriate? -- Question #2: Was the search for eligible studies thorough? -- Question #3: Was the validity of the included studies assessed? -- Question #4: Were the assessments of the studies reproducible? -- 6.3 Appraising the results -- Question #1: What are the overall results of the review? -- Question #2: How precise were the results? -- Question #3: Were the results similar from study to study? -- 6.4 Assessing applicability -- 6.5 Individualizing the results -- 6.6 Sharing the decision -- 6.7 Summary -- References -- Chapter 7 Evaluation of Clinical Practice Guidelines -- 7.1 Appraising directness -- 7.2 Appraising validity -- Question #1: Was the composition of the guideline panel appropriate? -- Question #2: Were conflicts of interest managed adequately? -- Question #3: Were there systematic reviews of evidence? -- Question #4: Were all important options and outcomes considered in making recommendations? -- Question #5: Were costs considered in making recommendations? -- Question #6: Were patients' values and preferences considered? -- Question #7: Were recommendations reached through consensus? -- 7.3 Appraising the results -- Question #1: What is the recommendation? -- Question #2: What is the level of evidence? -- Question #3: What is the strength of the recommendation? -- 7.4 Assessing applicability -- 7.5 Individualizing the recommendations -- 7.6 Sharing the decision -- 7.7 Summary -- References -- Chapter 8 Evaluation of Articles on Health Screening -- 8.1 Appraising directness -- Exceptions to the need for direct trials -- 8.2 Appraising validity -- 8.3 Appraising the results -- Question #1: How large was the treatment effect? -- Question #2: How precise were the estimates? -- 8.4 Assessing applicability -- 8.5 Individualizing the results -- 8.6 Sharing the decision 8.7 Summary -- References -- Chapter 9 Literature Searches -- 9.1 What are electronic databases? -- 9.2 The language of electronic databases -- 9.3 Steps in performing a literature search -- Step 1: Identify the concepts in your focused clinical question (P, E, O, and M) -- Step 2: Prioritize the concepts from most to least important -- Step 3: (a) Expand and (b) intersect each concept sequentially, until you obtain a manageable number of articles -- Step 4: Examine the yield for mishits and misses, and revise the search if necessary -- 9.4 Other ways to search -- Pre-appraised articles -- Push or pull technology -- To Google or not to Google -- 9.5 Summary -- References -- Index -- EULA Cover -- Title Page -- Copyright -- Contents -- List of Contributors -- Foreword to the First Edition -- Foreword to the Second Edition -- Preface -- Chapter 1 Introduction -- 1.1 The definition of EBM -- 1.2 The three skills of EBM -- Skill #1: Acquiring the evidence -- Skill #2: Appraising the evidence -- Skill #3: Applying the evidence -- 1.3 Summary -- 1.3 References -- Chapter 2 Evaluation of Articles on Therapy -- 2.1 Appraising directness -- 2.2 Appraising validity -- Question #1: Were patients randomly assigned to treatment groups? -- Question #2: Was allocation concealed? -- Question #3: Were baseline characteristics similar at the start of the trial? -- Question #4: Were patients blinded to treatment assignment? -- Question #5: Were caregivers blinded to treatment assignment? -- Question #6: Were outcome assessors blinded to treatment assignment? -- Question #7: Were all patients analyzed in the groups to which they were originally randomized? -- Question #8: Was follow-up rate adequate? -- Summary -- 2.3 Appraising the results -- Question #1: How large was the treatment effect? -- Question #2: How precise was the estimate of the treatment effect? -- 2.4 Assessing applicability -- 2.5 Individualizing the results -- 2.6 Sharing the decision -- 2.7 Summary -- References -- Chapter 3 Evaluation of Articles on Diagnosis -- 3.1 Appraising directness -- 3.2 Appraising validity -- Question #1: Was the reference standard an acceptable one? -- Question #2: Was "definition" of the index test and the reference standard independent? -- Question #3: Was "performance" of the index test and the reference standard independent? -- Question #4: Was "interpretation" of the index test and the reference standard independent? -- 3.3 Appraising the results -- Question #1: What were the likelihood ratios of the various test results? 3.4 Assessing applicability -- 3.5 Individualizing the results -- 3.6 Sharing the decision -- 3.7 Summary -- References -- Chapter 4 Evaluation of Articles on Harm -- 4.1 Appraising directness -- 4.2 Appraising validity -- Question #1: Did the exposure in question precede the undesirable outcome? -- Question #2: Were important prognostic factors balanced at the time of exposure? If not, were statistical adjustments made for these factors? -- Question #3: Were unbiased criteria used to determine exposure in all patients? -- Question #4: Were unbiased criteria used to detect the outcome in all patients? -- Question #5: Was the follow-up rate adequate? -- 4.3 Appraising the results -- Question #1: How strong is the association between exposure and outcome? -- Question #2: How precise is the estimate of the risk? -- 4.4 Assessing applicability -- Panel A. 2 × 2 table for RCTs and cohort studies -- Panel B. 2 × 2 table for case-control studies -- 4.5 Individualizing the results -- 4.6 Sharing the decision -- 4.7 Summary -- References -- Chapter 5 Evaluation of Articles on Prognosis -- 5.1 Appraising directness -- 5.2 Appraising validity -- Question #1: Were all important prognostic factors considered? -- Question #2: Were unbiased criteria used to detect the outcome in all patients? -- Question #3: Was follow-up rate adequate? -- Question #4: If clinical prediction rules are being tested, was a separate validation study done? -- 5.3 Appraising the results -- Question #1: How likely are the outcomes over time? -- Question #2: How precise are the estimates of likelihood? -- 5.4 Assessing applicability -- 5.5 Individualizing the results -- 5.6 Sharing the decision -- 5.7 Summary -- References -- Chapter 6 Evaluation of Systematic Reviews -- 6.1 Appraising directness -- 6.2 Appraising validity |
| Title | Painless Evidence-Based Medicine |
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