Mo Single-Atom Nanozyme Anchored to the 2D N‑Doped Carbon Film: Catalytic Mechanism, Visual Monitoring of Choline, and Evaluation of Intracellular ROS Generation

• Published in: ACS applied materials & interfaces Vol. 15; no. 30; pp. 36124 - 36134
• Main Authors: Sun, Qijun, Xu, Xiaoyu, Liu, Song, Wu, Xinzhao, Yin, Chenhui, Wu, Meng, Chen, Yuxue, Niu, Na, Chen, Ligang, Bai, Fuquan
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 02.08.2023
• Subjects: blood serum; Carbon; Catalysis; Choline; choline oxidase; density functional theory; detection limit; Energy, Environmental, and Catalysis Applications; Humans; Hydrogen Peroxide; mobile telephones; neoplasms; pyrolysis; Reactive Oxygen Species; toxicity; Mo single-atom nanozyme; peroxidase-like mimetic; intratumoral •OH generation; visual sensing of choline; density functional theory

Single-atom nanozymes (SANs) have attracted great attention in constructing devices for instant biosensing due to their excellent stability and atom utilization. Here, Mo atoms were immobilized in 2D nitrogen-doped carbon films by cascade-anchored one-pot pyrolysis to obtain Mo single-atom nanozyme...