Poly(l-lysine)-g-Poly(ethylene glycol) Layers on Metal Oxide Surfaces:  Attachment Mechanism and Effects of Polymer Architecture on Resistance to Protein Adsorption

• Published in: The journal of physical chemistry. B Vol. 104; no. 14; pp. 3298 - 3309
• Main Authors: Kenausis, Gregory L, Vörös, Janos, Elbert, Donald L, Huang, Ningping, Hofer, Rolf, Ruiz-Taylor, Laurence, Textor, Marcus, Hubbell, Jeffrey A, Spencer, Nicholas D
• Format: Journal Article
• Language: English
• Published: American Chemical Society 13.04.2000

The generation of surfaces and interfaces that are able to withstand protein adsorption is a major challenge in the design of blood-contacting materials for both medical implants and bioaffinity sensors. Poly(ethylene glycol)-derived materials are generally considered to be particularly effective ca...